Ccl12 - C-C motif chemokine ligand 12 Gene

Also Known as MCP-5

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 287562

Summary

Predicted to enable CCR2 Chemokine Receptor binding activity and chemokine activity. Involved in negative regulation of leukocyte proliferation and positive regulation of leukocyte migration. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in several diseases, including Henoch-Schoenlein purpura; aggressive periodontitis; autoimmune disease (multiple); gastrointestinal system Cancer (multiple); and tuberculosis (multiple). Orthologous to several human genes including CCL8 (C-C motif chemokine ligand 8). [provided by Alliance of Genome Resources, Apr 2022]

Ccl12 Products (1)

mRNA Protein Name
NM_001105822.1 NP_001099292.1 C-C motif chemokine ligand 12 precursor
Protein Preferred Names Protein Names

C-C motif chemokine ligand 12

  • chemokine (C-C motif) ligand 12

  • monocyte chemotactic protein 5

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B0673 Pirfenidone Inhibitor 99.99% Yes
HY-B0673R Pirfenidone (Standard) Inhibitor 99.97% Unkown

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-B0673S1 Deupirfenidone 99.93% Phase 2

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-B0673S Pirfenidone-d5 Inhibitor 98.88% Unkown