2. Gene
  3. Ccl12 - C-C motif chemokine ligand 12 Gene

Ccl12 - C-C motif chemokine ligand 12 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as MCP-5

Gene ID: 287562 | Gene type: protein coding

About Ccl12

Summary

Predicted to enable CCR2 Chemokine Receptor binding activity and chemokine activity. Involved in negative regulation of leukocyte proliferation and positive regulation of leukocyte migration. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in several diseases, including Henoch-Schoenlein purpura; aggressive periodontitis; autoimmune disease (multiple); gastrointestinal system Cancer (multiple); and tuberculosis (multiple). Orthologous to several human genes including CCL8 (C-C motif chemokine ligand 8). [provided by Alliance of Genome Resources, Apr 2022]

Ccl12 Products(1)

mRNA Protein Name
NM_001105822.1 NP_001099292.1 C-C motif chemokine ligand 12 precursor
Protein Preferred Names Protein Names

C-C motif chemokine ligand 12

chemokine (C-C motif) ligand 12

monocyte chemotactic protein 5

Related Agents

Approval
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B0673 Pirfenidone Inhibitor 99.99% Yes
HY-B0673R Pirfenidone (Standard) Inhibitor 99.97% Unkown
Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-B0673S1 Deupirfenidone 99.60% Phase 2
Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B0673S Pirfenidone-d5 Inhibitor 98.88% Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus Ccl12 NCBI