Chfr - checkpoint with forkhead and ring finger domains Gene

Predicted to enable nucleotide binding activity and ubiquitin protein Ligase activity. Predicted to be involved in cellular protein metabolic process and negative regulation of cell cycle phase transition. Predicted to act upstream of or within mitotic cell cycle; positive regulation of cellular protein metabolic process; and protein destabilization. Predicted to be located in PML body. Predicted to be active in nucleus. Orthologous to human CHFR (checkpoint with forkhead and ring finger domains). [provided by Alliance of Genome Resources, Apr 2022]