Arhgap44 - Rho GTPase activating protein 44 Gene

Also Known as RGD1305664

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 303222

Summary

Enables GTPase activator activity. Involved in negative regulation of filopodium assembly and regulation of GTPase activity. Located in dendrite. Is active in glutamatergic synapse; postsynaptic density; and presynaptic active zone. Orthologous to human ARHGAP44 (Rho GTPase activating protein 44). [provided by Alliance of Genome Resources, Apr 2022]

Arhgap44 Products (7)

mRNA Protein Name
XM_039087289.1 XP_038943217.1 rho GTPase-activating protein 44 isoform X6
XM_039087286.1 XP_038943214.1 rho GTPase-activating protein 44 isoform X2
XM_039087285.1 XP_038943213.1 rho GTPase-activating protein 44 isoform X1
XM_039087287.1 XP_038943215.1 rho GTPase-activating protein 44 isoform X4
XM_039087291.1 XP_038943219.1 rho GTPase-activating protein 44 isoform X7
XM_006246834.4 XP_006246896.1 rho GTPase-activating protein 44 isoform X3
XM_039087288.1 XP_038943216.1 rho GTPase-activating protein 44 isoform X5

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables GTPase activator activity IDA
IDA: Inferred from direct assay
25498153 RGD
Biological Process GO Annotation Evidence References Source
involved in negative regulation of filopodium assembly IDA
IDA: Inferred from direct assay
25498153 RGD
involved in negative regulation of filopodium assembly IMP
IMP: Inferred from mutant phenotype
25498153 RGD
Cellular Component GO Annotation Evidence References Source
located in dendrite IDA
IDA: Inferred from direct assay
23739967 RGD
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
23739967 RGD
located in postsynapse IDA
IDA: Inferred from direct assay
23739967 RGD
is active in postsynaptic density IDA
IDA: Inferred from direct assay
23739967 RGD
located in presynapse IDA
IDA: Inferred from direct assay
23739967 RGD
is active in presynaptic active zone IDA
IDA: Inferred from direct assay
23739967 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

rho GTPase-activating protein 44

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00937 ARHGAP44 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Arhgap44 NCBI NCBI:9912