2. Gene
  3. Arhgap44 - Rho GTPase activating protein 44 Gene

Arhgap44 - Rho GTPase activating protein 44 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as RGD1305664

Gene ID: 303222 | Gene type: protein coding

About Arhgap44

Summary

Enables GTPase activator activity. Involved in negative regulation of filopodium assembly and regulation of GTPase activity. Located in dendrite. Is active in glutamatergic synapse; postsynaptic density; and presynaptic active zone. Orthologous to human ARHGAP44 (Rho GTPase activating protein 44). [provided by Alliance of Genome Resources, Apr 2022]

Arhgap44 Products(7)

mRNA Protein Name
XM_039087289.1 XP_038943217.1 rho GTPase-activating protein 44 isoform X6
XM_039087286.1 XP_038943214.1 rho GTPase-activating protein 44 isoform X2
XM_039087285.1 XP_038943213.1 rho GTPase-activating protein 44 isoform X1
XM_039087287.1 XP_038943215.1 rho GTPase-activating protein 44 isoform X4
XM_039087291.1 XP_038943219.1 rho GTPase-activating protein 44 isoform X7
XM_006246834.4 XP_006246896.1 rho GTPase-activating protein 44 isoform X3
XM_039087288.1 XP_038943216.1 rho GTPase-activating protein 44 isoform X5
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables GTPase activator activity IDA
IDA: Inferred from direct assay
25498153 RGD
Biological Process GO Annotation Evidence Reference Source
involved in negative regulation of filopodium assembly IDA
IDA: Inferred from direct assay
25498153 RGD
involved in negative regulation of filopodium assembly IMP
IMP: Inferred from mutant phenotype
25498153 RGD
Cellular Component GO Annotation Evidence Reference Source
located in dendrite IDA
IDA: Inferred from direct assay
23739967 RGD
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
23739967 RGD
located in postsynapse IDA
IDA: Inferred from direct assay
23739967 RGD
is active in postsynaptic density IDA
IDA: Inferred from direct assay
23739967 RGD
located in presynapse IDA
IDA: Inferred from direct assay
23739967 RGD
is active in presynaptic active zone IDA
IDA: Inferred from direct assay
23739967 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

rho GTPase-activating protein 44

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00937 ARHGAP44 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Arhgap44 NCBI NCBI:9912