2. Gene
  3. Abi3 - ABI family, member 3 Gene

Abi3 - ABI family, member 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 303476 | Gene type: protein coding

About Abi3

Summary

Predicted to enable SH3 domain binding activity and identical protein binding activity. Predicted to be involved in several processes, including defense response to tumor cell; negative regulation of lamellipodium assembly; and positive regulation of cellular senescence. Predicted to be located in cytoplasm. Predicted to be part of SCAR complex. Predicted to be active in lamellipodium. Orthologous to human ABI3 (ABI family member 3). [provided by Alliance of Genome Resources, Apr 2022]

Abi3 Products(1)

mRNA Protein Name
NM_001013118.1 NP_001013136.1 ABI gene family member 3
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in modification of postsynaptic actin cytoskeleton IDA
IDA: Inferred from direct assay
22485184 RGD
involved in modification of postsynaptic actin cytoskeleton IEP
IEP: Inferred from expression pattern
22485184 RGD
involved in modification of postsynaptic actin cytoskeleton IMP
IMP: Inferred from mutant phenotype
22485184 RGD
Cellular Component GO Annotation Evidence Reference Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
22485184 RGD
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
22485184 RGD
is active in postsynapse IDA
IDA: Inferred from direct assay
22485184 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ABI gene family member 3

ABI gene family, member 3

NESH protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00101 ABI3BP Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS00100 ABI3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Abi3 NCBI NCBI:51225