Arhgap12 - Rho GTPase activating protein 12 Gene

Rattus norvegicus

Gene ID: 307016 | Gene type: protein coding

About Arhgap12

Summary

Predicted to enable GTPase activator activity. Predicted to be involved in several processes, including negative regulation of small GTPase mediated signal transduction; phagocytosis, engulfment; and regulation of GTPase activity. Predicted to be located in phagocytic cup. Predicted to be active in cytoplasm. Orthologous to human ARHGAP12 (Rho GTPase activating protein 12). [provided by Alliance of Genome Resources, Apr 2022]

Arhgap12 Products(1)

mRNA	Protein	Name
NM_001107357.2	NP_001100827.2	rho GTPase-activating protein 12

Gene Ontology

Biological Process
Cellular Component

Biological Process GO Annotation	Evidence	Reference	Source
involved in regulation of postsynapse assembly	IDA IDA: Inferred from direct assay	26854232	RGD
involved in regulation of postsynapse assembly	IMP IMP: Inferred from mutant phenotype	26854232	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
is active in glutamatergic synapse	IDA IDA: Inferred from direct assay	26854232	RGD
is active in glutamatergic synapse	IMP IMP: Inferred from mutant phenotype	26854232	RGD
is active in postsynapse	IDA IDA: Inferred from direct assay	26854232	RGD
is active in postsynapse	IMP IMP: Inferred from mutant phenotype	26854232	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

rho GTPase-activating protein 12

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00915	ARHGAP12 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Arhgap12	NCBI	NCBI:94134

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