Dtna - dystrobrevin, alpha Gene

Also Known as Dtna-ps1; RGD1561985

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 307548

Summary

Enables PDZ domain binding activity and Phosphatase binding activity. Predicted to be involved in synaptic signaling. Located in axon; cytoplasm; and sarcolemma. Is extrinsic component of cytoplasmic side of plasma membrane. Human ortholog(s) of this gene implicated in cardiomyopathy and left ventricular noncompaction. Orthologous to human DTNA (dystrobrevin alpha). [provided by Alliance of Genome Resources, Apr 2022]

Dtna Products (24)

mRNA Protein Name
XM_039097222.1 XP_038953150.1 dystrobrevin alpha isoform X6
XM_039097219.1 XP_038953147.1 dystrobrevin alpha isoform X3
XM_017601078.2 XP_017456567.2 dystrobrevin alpha isoform X3
XM_039097224.1 XP_038953152.1 dystrobrevin alpha isoform X8
XM_039097218.1 XP_038953146.1 dystrobrevin alpha isoform X2
XM_039097221.1 XP_038953149.1 dystrobrevin alpha isoform X5
XM_039097223.1 XP_038953151.1 dystrobrevin alpha isoform X7
XM_039097220.1 XP_038953148.1 dystrobrevin alpha isoform X4
XM_039097235.1 XP_038953163.1 dystrobrevin alpha isoform X23
XM_039097229.1 XP_038953157.1 dystrobrevin alpha isoform X13
XM_039097234.1 XP_038953162.1 dystrobrevin alpha isoform X22
XM_039097232.1 XP_038953160.1 dystrobrevin alpha isoform X16
XM_039097225.1 XP_038953153.1 dystrobrevin alpha isoform X9
XM_039097228.1 XP_038953156.1 dystrobrevin alpha isoform X12
XM_039097231.1 XP_038953159.1 dystrobrevin alpha isoform X15
XM_039097227.1 XP_038953155.1 dystrobrevin alpha isoform X11
XM_039097226.1 XP_038953154.1 dystrobrevin alpha isoform X10
XM_039097230.1 XP_038953158.1 dystrobrevin alpha isoform X14
XM_017601080.2 XP_017456569.2 dystrobrevin alpha isoform X17
XM_039097233.1 XP_038953161.1 dystrobrevin alpha isoform X19
XM_017601081.2 XP_017456570.2 dystrobrevin alpha isoform X18
XM_017601082.2 XP_017456571.2 dystrobrevin alpha isoform X20
XM_017601083.2 XP_017456572.2 dystrobrevin alpha isoform X21
XM_039097217.1 XP_038953145.1 dystrobrevin alpha isoform X1

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables PDZ domain binding IPI
IPI: Inferred from physical interaction
15024025 RGD
enables phosphatase binding IDA
IDA: Inferred from direct assay
17610895 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
10984432 RGD
Cellular Component GO Annotation Evidence References Source
located in axon IDA
IDA: Inferred from direct assay
11053293 RGD
located in cell projection IDA
IDA: Inferred from direct assay
10739890 RGD
located in extrinsic component of cytoplasmic side of plasma membrane IDA
IDA: Inferred from direct assay
11053293 RGD
located in sarcolemma IDA
IDA: Inferred from direct assay
12416719 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

dystrobrevin alpha

  • dystrobrevin alpha, pseudogene 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04035 DTNA Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dtna NCBI NCBI:1837