E2f8 - E2F transcription factor 8 Gene

Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and identical protein binding activity. Predicted to be involved in several processes, including hepatocyte differentiation; regulation of cellular macromolecule biosynthetic process; and trophoblast giant cell differentiation. Predicted to act upstream of or within cell population proliferation. Predicted to be located in cytosol; nucleolus; and nucleoplasm. Predicted to be part of RNA polymerase II transcription regulator complex. Orthologous to human E2F8 (E2F transcription factor 8). [provided by Alliance of Genome Resources, Apr 2022]