Sgip1 - SH3GL interacting endocytic adaptor 1 Gene

Rattus norvegicus

Also known as RGD1564957

Gene ID: 313413 | Gene type: protein coding

About Sgip1

Summary

Enables tubulin binding activity. Involved in several processes, including energy homeostasis; positive regulation of eating behavior; and response to dietary excess. Located in terminal bouton. Is active in presynapse. Orthologous to human SGIP1 (SH3GL interacting endocytic adaptor 1). [provided by Alliance of Genome Resources, Apr 2022]

Sgip1 Products(1)

mRNA	Protein	Name
NM_001376936.1	NP_001363865.1	SH3-containing GRB2-like protein 3-interacting protein 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables tubulin binding	IPI IPI: Inferred from physical interaction	17626015	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in energy homeostasis	IMP IMP: Inferred from mutant phenotype	15919751	RGD
involved in positive regulation of eating behavior	IMP IMP: Inferred from mutant phenotype	15919751	RGD
involved in positive regulation of feeding behavior	IMP IMP: Inferred from mutant phenotype	15919751	RGD
involved in positive regulation of multicellular organism growth	IMP IMP: Inferred from mutant phenotype	15919751	RGD
involved in response to dietary excess	IMP IMP: Inferred from mutant phenotype	15919751	RGD
involved in response to starvation	IEP IEP: Inferred from expression pattern	15919751	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
is active in presynapse	IDA IDA: Inferred from direct assay	26970018	RGD
is active in presynapse	IMP IMP: Inferred from mutant phenotype	26970018	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

SH3-containing GRB2-like protein 3-interacting protein 1

Endophilin-3-interacting protein

SH3-domain GRB2-like (endophilin) interacting protein 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12797	SGIP1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Sgip1	NCBI	NCBI:84251

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