Amigo3 - adhesion molecule with Ig like domain 3 Gene

Rattus norvegicus

Gene ID: 316003 | Gene type: protein coding

About Amigo3

Summary

Involved in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; negative regulation of neuron projection development; and nervous system development. Predicted to be integral component of membrane. Biomarker of sciatic neuropathy. Orthologous to human AMIGO3 (adhesion molecule with Ig like domain 3). [provided by Alliance of Genome Resources, Apr 2022]

Amigo3 Products(1)

mRNA	Protein	Name
NM_178144.1	NP_835280.1	amphoterin-induced protein 3 precursor

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	12629050	RGD
enables protein-containing complex binding	IPI IPI: Inferred from physical interaction	23613963	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	IPI IPI: Inferred from physical interaction	12629050	RGD
involved in negative regulation of neuron projection development	IMP IMP: Inferred from mutant phenotype	23613963	RGD
involved in nervous system development	IDA IDA: Inferred from direct assay	12629050	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

amphoterin-induced protein 3

AMIGO-3	alivin-3
amphoterin induced gene and ORF 3	transmembrane protein AMIGO3

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00659	AMIGO3 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Amigo3	NCBI	NCBI:386724

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