AMIGO3 - adhesion molecule with Ig like domain 3 Gene

Homo sapiens

Also known as ALI3; AMIGO-3

Gene ID: 386724 | Gene type: protein coding

About AMIGO3

Cytogenetic location: 3p21.31 Genomic coordinates (GRCh38): 3:49,716,829-49,719,684 (from NCBI)

This gene has 1 transcript (splice variant), 251 orthologues and 2 paralogues.

Summary

Predicted to be involved in brain development and heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules. Predicted to act upstream of or within positive regulation of synapse assembly. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

AMIGO3 Products(1)

mRNA	Protein	Name
NM_198722.3	NP_942015.1	amphoterin-induced protein 3 precursor

AMIGO3 Protein Structure

LRR_8

0
100
200
300
400
504 a.a.

Protein Preferred Names

Protein Names

amphoterin-induced protein 3

alivin-3

Related Diseases

Diseases

Alias

Mirror Movements 1

Congenital Mirror Movement Disorder	Bimanual Synergia
Congenital Mirror Movements	Familial Congenital Controlateral Synkinesia
Familial Congenital Mirror Movements	Hereditary Congenital Controlateral Synkinesia
Hereditary Congenital Mirror Movements	Isolated Congenital Controlateral Synkinesia
Isolated Congenital Mirror Movements	Mirror Movements
MRMV1	Mirror Movements 1 And/Or Agenesis Of The Corpus Callosum
Mirror Movements, Congenital	Bimanual Synkinesis
Cmm	Mirror Movements, Type 1

Urofacial Syndrome 1

Urofacial Syndrome	Ochoa Syndrome
Hydronephrosis With Peculiar Facial Expression	Ufs
Inverted Smile And Occult Neuropathic Bladder	Partial Facial Palsy With Urinary Abnormalities
UFS1	Urofacial Ochoa'S Syndrome
Urofacial Syndrome Type 1	Facial Palsy, Partial, With Urinary Abnormalities
Hydronephrosis-Inverted Smile	Inverted Smile-Neurogenic Bladder
Hydronephrosis-Inverted Smile Syndrome	Inverted Smile-Neurogenic Bladder Syndrome
Partial Facial Palsy Partial With Urinary Abnormalities	Urologic Diseases

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00659	AMIGO3 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	AMIGO3	VGNC	VGNC:37833
Felis catus	AMIGO3	VGNC	VGNC:59767
Macaca mulatta	AMIGO3	VGNC	VGNC:69681
Rattus norvegicus	AMIGO3	RGD	RGD:631413
Mus musculus	AMIGO3	MGD	MGI:2444854
Bos taurus	AMIGO3	VGNC	VGNC:25867

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