AMIGO3 - adhesion molecule with Ig like domain 3 Gene

Also Known as ALI3; AMIGO-3

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 386724

About AMIGO3

Cytogenetic location: 3p21.31 Genomic coordinates (GRCh38): 3:49,716,829-49,719,684 (from NCBI)

This gene has 1 transcript (splice variant), 251 orthologues and 2 paralogues.

Summary

Predicted to be involved in brain development and heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules. Predicted to act upstream of or within positive regulation of synapse assembly. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

AMIGO3 Products (1)

mRNA	Protein	Name
NM_198722.3	NP_942015.1	amphoterin-induced protein 3 precursor

AMIGO3 Protein Structure

LRR_8

0
100
200
300
400
504 a.a.

Protein Preferred Names	Protein Names
amphoterin-induced protein 3	alivin-3

Related Diseases

Diseases	Alias
Mirror Movements 1	Congenital Mirror Movement Disorder Bimanual Synergia Congenital Mirror Movements Familial Congenital Controlateral Synkinesia Familial Congenital Mirror Movements Hereditary Congenital Controlateral Synkinesia Hereditary Congenital Mirror Movements Isolated Congenital Controlateral Synkinesia Isolated Congenital Mirror Movements Mirror Movements MRMV1 Mirror Movements 1 And/Or Agenesis Of The Corpus Callosum Mirror Movements, Congenital Bimanual Synkinesis Cmm Mirror Movements, Type 1
Urofacial Syndrome 1	Urofacial Syndrome Ochoa Syndrome Hydronephrosis With Peculiar Facial Expression Ufs Inverted Smile And Occult Neuropathic Bladder Partial Facial Palsy With Urinary Abnormalities UFS1 Urofacial Ochoa'S Syndrome Urofacial Syndrome Type 1 Facial Palsy, Partial, With Urinary Abnormalities Hydronephrosis-Inverted Smile Inverted Smile-Neurogenic Bladder Hydronephrosis-Inverted Smile Syndrome Inverted Smile-Neurogenic Bladder Syndrome Partial Facial Palsy Partial With Urinary Abnormalities Urologic Diseases

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00659	AMIGO3 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	AMIGO3	VGNC	VGNC:37833
Felis catus	AMIGO3	VGNC	VGNC:59767
Macaca mulatta	AMIGO3	VGNC	VGNC:69681
Rattus norvegicus	AMIGO3	RGD	RGD:631413
Mus musculus	AMIGO3	MGD	MGI:2444854
Bos taurus	AMIGO3	VGNC	VGNC:25867