Pla2g4e - phospholipase A2, group IVE Gene

Also Known as C230096D22; Pla2epsilon; 2310026J01Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 329502

Summary

Enables several functions, including phosphatidylinositol phosphate binding activity; phosphatidylinositol-3,4-bisphosphate binding activity; and Phospholipase A2 activity. Involved in N-acylphosphatidylethanolamine metabolic process and positive regulation of endocytic recycling. Located in early endosome membrane; lysosomal membrane; and plasma membrane. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human PLA2G4E (Phospholipase A2 group IVE). [provided by Alliance of Genome Resources, Apr 2022]

Pla2g4e Products (4)

mRNA Protein Name
NM_001363090.1 NP_001350019.1 cytosolic phospholipase A2 epsilon isoform 2
NM_001363091.1 NP_001350020.1 cytosolic phospholipase A2 epsilon isoform 3
NM_001395470.1 NP_001382399.1 cytosolic phospholipase A2 epsilon isoform 4
NM_177845.4 NP_808513.2 cytosolic phospholipase A2 epsilon isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables N-acyltransferase activity IDA
IDA: Inferred from direct assay
27399000 MGI
enables phosphatidylinositol-3,4,5-trisphosphate binding IDA
IDA: Inferred from direct assay
24413173 MGI
enables phosphatidylinositol-3,4-bisphosphate binding IDA
IDA: Inferred from direct assay
24413173 MGI
enables phosphatidylinositol-3,5-bisphosphate binding IDA
IDA: Inferred from direct assay
24413173 MGI
enables phosphatidylinositol-3-phosphate binding IDA
IDA: Inferred from direct assay
24413173 MGI
enables phosphatidylinositol-4,5-bisphosphate binding IDA
IDA: Inferred from direct assay
24413173 MGI
enables phosphatidylinositol-4-phosphate binding IDA
IDA: Inferred from direct assay
24413173 MGI
enables phosphatidylinositol-5-phosphate binding IDA
IDA: Inferred from direct assay
24413173 MGI
enables phospholipase A2 activity IDA
IDA: Inferred from direct assay
15866882 MGI
Biological Process GO Annotation Evidence References Source
involved in N-acylphosphatidylethanolamine metabolic process IDA
IDA: Inferred from direct assay
27399000 MGI
involved in positive regulation of endocytic recycling IMP
IMP: Inferred from mutant phenotype
24413173 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
15866882 MGI
located in early endosome membrane IDA
IDA: Inferred from direct assay
24413173 MGI
located in lysosomal membrane IDA
IDA: Inferred from direct assay
29447909 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
24413173 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cytosolic phospholipase A2 epsilon

  • cPLA2-epsilon

  • calcium-dependent N-acyltransferase

  • phospholipase A2, group 4E

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10630 PLA2G4E Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pla2g4e NCBI NCBI:123745