2. Gene
  3. Pla2g4e - phospholipase A2, group IVE Gene

Pla2g4e - phospholipase A2, group IVE Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as C230096D22; Pla2epsilon; 2310026J01Rik

Gene ID: 329502 | Gene type: protein coding

About Pla2g4e

Summary

Enables several functions, including phosphatidylinositol phosphate binding activity; phosphatidylinositol-3,4-bisphosphate binding activity; and Phospholipase A2 activity. Involved in N-acylphosphatidylethanolamine metabolic process and positive regulation of endocytic recycling. Located in early endosome membrane; lysosomal membrane; and plasma membrane. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human PLA2G4E (Phospholipase A2 group IVE). [provided by Alliance of Genome Resources, Apr 2022]

Pla2g4e Products(4)

mRNA Protein Name
NM_001363090.1 NP_001350019.1 cytosolic phospholipase A2 epsilon isoform 2
NM_001363091.1 NP_001350020.1 cytosolic phospholipase A2 epsilon isoform 3
NM_001395470.1 NP_001382399.1 cytosolic phospholipase A2 epsilon isoform 4
NM_177845.4 NP_808513.2 cytosolic phospholipase A2 epsilon isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables N-acyltransferase activity IDA
IDA: Inferred from direct assay
27399000 MGI
enables phosphatidylinositol-3,4,5-trisphosphate binding IDA
IDA: Inferred from direct assay
24413173 MGI
enables phosphatidylinositol-3,4-bisphosphate binding IDA
IDA: Inferred from direct assay
24413173 MGI
enables phosphatidylinositol-3,5-bisphosphate binding IDA
IDA: Inferred from direct assay
24413173 MGI
enables phosphatidylinositol-3-phosphate binding IDA
IDA: Inferred from direct assay
24413173 MGI
enables phosphatidylinositol-4,5-bisphosphate binding IDA
IDA: Inferred from direct assay
24413173 MGI
enables phosphatidylinositol-4-phosphate binding IDA
IDA: Inferred from direct assay
24413173 MGI
enables phosphatidylinositol-5-phosphate binding IDA
IDA: Inferred from direct assay
24413173 MGI
enables phospholipase A2 activity IDA
IDA: Inferred from direct assay
15866882 MGI
Biological Process GO Annotation Evidence Reference Source
involved in N-acylphosphatidylethanolamine metabolic process IDA
IDA: Inferred from direct assay
27399000 MGI
involved in positive regulation of endocytic recycling IMP
IMP: Inferred from mutant phenotype
24413173 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
15866882 MGI
located in early endosome membrane IDA
IDA: Inferred from direct assay
24413173 MGI
located in lysosomal membrane IDA
IDA: Inferred from direct assay
29447909 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
24413173 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cytosolic phospholipase A2 epsilon

cPLA2-epsilon

calcium-dependent N-acyltransferase

phospholipase A2, group 4E

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10630 PLA2G4E Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pla2g4e NCBI NCBI:123745