Trim46 - tripartite motif-containing 46 Gene

Also Known as TRIFIC

Species: Mus musculus

Gene Type: protein coding
Gene ID: 360213

Summary

Predicted to enable microtubule binding activity. Involved in regulation of protein localization. Acts upstream of or within several processes, including anterograde synaptic vesicle transport; generation of neurons; and protein localization to axon. Located in axon initial segment and proximal neuron projection. Orthologous to human TRIM46 (tripartite motif containing 46). [provided by Alliance of Genome Resources, Apr 2022]

Trim46 Products (2)

mRNA Protein Name
NM_001039466.1 NP_001034555.1 tripartite motif-containing protein 46 isoform 3
NM_183037.2 NP_898858.1 tripartite motif-containing protein 46 isoform 2

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within anterograde synaptic vesicle transport IMP
IMP: Inferred from mutant phenotype
26671463 MGI
acts upstream of or within axonogenesis IDA
IDA: Inferred from direct assay
26671463 MGI
acts upstream of or within axonogenesis IMP
IMP: Inferred from mutant phenotype
26671463 MGI
acts upstream of or within microtubule bundle formation IMP
IMP: Inferred from mutant phenotype
26671463 MGI
acts upstream of or within microtubule cytoskeleton organization IMP
IMP: Inferred from mutant phenotype
26671463 MGI
acts upstream of or within neuron migration IDA
IDA: Inferred from direct assay
26671463 MGI
acts upstream of or within neuron migration IMP
IMP: Inferred from mutant phenotype
26671463 MGI
acts upstream of or within protein localization to axon IMP
IMP: Inferred from mutant phenotype
26671463 MGI
involved in regulation of protein localization IMP
IMP: Inferred from mutant phenotype
28426968 MGI
Cellular Component GO Annotation Evidence References Source
located in axon initial segment IDA
IDA: Inferred from direct assay
26671463 MGI
located in main axon IDA
IDA: Inferred from direct assay
28426968 MGI
located in proximal neuron projection IMP
IMP: Inferred from mutant phenotype
26671463 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tripartite motif-containing protein 46

  • geneY

  • tripartite, fibronectin type III and C-terminal SPRY motif-containing

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15050 TRIM46 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Trim46 NCBI NCBI:80128