ANK2 - Ank2 ankyrin 2 Gene
Also Known as Ank3
Species: Rattus norvegicus
Gene Type: protein coding
Gene ID: 362036
Summary
Enables protein kinase binding activity and transmembrane transporter binding activity. A structural constituent of Cytoskeleton. Involved in paranodal junction assembly and response to methylmercury. Located in several cellular components, including cytoskeleton; membrane raft; and neuron projection. Biomarker of transient cerebral ischemia. Human ortholog(s) of this gene implicated in ankyrin-B-related cardiac arrhythmia; atrial fibrillation; long QT syndrome; and sick sinus syndrome. Orthologous to human ANK2 (ankyrin 2). [provided by Alliance of Genome Resources, Apr 2022]
ANK2 Products (50)
| mRNA | Protein | Name |
|---|---|---|
| XM_039104011.1 | XP_038959939.1 | ankyrin-2 isoform X18 |
| XM_039104027.1 | XP_038959955.1 | ankyrin-2 isoform X32 |
| XM_039104001.1 | XP_038959929.1 | ankyrin-2 isoform X9 |
| XM_039104015.1 | XP_038959943.1 | ankyrin-2 isoform X21 |
| XM_039104020.1 | XP_038959948.1 | ankyrin-2 isoform X26 |
| XM_039104008.1 | XP_038959936.1 | ankyrin-2 isoform X15 |
| XM_039103996.1 | XP_038959924.1 | ankyrin-2 isoform X4 |
| XM_039104017.1 | XP_038959945.1 | ankyrin-2 isoform X23 |
| XM_039104025.1 | XP_038959953.1 | ankyrin-2 isoform X30 |
| XM_039104014.1 | XP_038959942.1 | ankyrin-2 isoform X20 |
| XM_039104019.1 | XP_038959947.1 | ankyrin-2 isoform X25 |
| XM_039104018.1 | XP_038959946.1 | ankyrin-2 isoform X24 |
| XM_039104003.1 | XP_038959931.1 | ankyrin-2 isoform X10 |
| XM_039103997.1 | XP_038959925.1 | ankyrin-2 isoform X5 |
| XM_039103998.1 | XP_038959926.1 | ankyrin-2 isoform X6 |
| XM_039103993.1 | XP_038959921.1 | ankyrin-2 isoform X1 |
| XM_039103994.1 | XP_038959922.1 | ankyrin-2 isoform X2 |
| XM_039104016.1 | XP_038959944.1 | ankyrin-2 isoform X22 |
| XM_039104004.1 | XP_038959932.1 | ankyrin-2 isoform X11 |
| XM_039103995.1 | XP_038959923.1 | ankyrin-2 isoform X3 |
| XM_039104012.1 | XP_038959940.1 | ankyrin-2 isoform X19 |
| XM_039104009.1 | XP_038959937.1 | ankyrin-2 isoform X16 |
| XM_039104000.1 | XP_038959928.1 | ankyrin-2 isoform X8 |
| XM_039104021.1 | XP_038959949.1 | ankyrin-2 isoform X27 |
| XM_039104007.1 | XP_038959935.1 | ankyrin-2 isoform X14 |
| XM_039104005.1 | XP_038959933.1 | ankyrin-2 isoform X12 |
| XM_039104022.1 | XP_038959950.1 | ankyrin-2 isoform X28 |
| XM_039104023.1 | XP_038959951.1 | ankyrin-2 isoform X29 |
| XM_039104032.1 | XP_038959960.1 | ankyrin-2 isoform X37 |
| XM_039104031.1 | XP_038959959.1 | ankyrin-2 isoform X36 |
| XM_039104039.1 | XP_038959967.1 | ankyrin-2 isoform X43 |
| XM_039104037.1 | XP_038959965.1 | ankyrin-2 isoform X41 |
| XM_039104043.1 | XP_038959971.1 | ankyrin-2 isoform X47 |
| XM_039104046.1 | XP_038959974.1 | ankyrin-2 isoform X50 |
| XM_039104040.1 | XP_038959968.1 | ankyrin-2 isoform X44 |
| XM_039104038.1 | XP_038959966.1 | ankyrin-2 isoform X42 |
| XM_039104044.1 | XP_038959972.1 | ankyrin-2 isoform X48 |
| XM_039104045.1 | XP_038959973.1 | ankyrin-2 isoform X49 |
| XM_039104042.1 | XP_038959970.1 | ankyrin-2 isoform X46 |
| XM_039103999.1 | XP_038959927.1 | ankyrin-2 isoform X7 |
| XM_039104034.1 | XP_038959962.1 | ankyrin-2 isoform X39 |
| XM_039104029.1 | XP_038959957.1 | ankyrin-2 isoform X34 |
| XM_039104036.1 | XP_038959964.1 | ankyrin-2 isoform X40 |
| XM_039104030.1 | XP_038959958.1 | ankyrin-2 isoform X35 |
| XM_039104041.1 | XP_038959969.1 | ankyrin-2 isoform X45 |
| XM_039104033.1 | XP_038959961.1 | ankyrin-2 isoform X38 |
| XM_039104028.1 | XP_038959956.1 | ankyrin-2 isoform X33 |
| XM_039104010.1 | XP_038959938.1 | ankyrin-2 isoform X17 |
| XM_039104006.1 | XP_038959934.1 | ankyrin-2 isoform X13 |
| XM_039104026.1 | XP_038959954.1 | ankyrin-2 isoform X31 |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
14593108 | RGD |
| enables protein kinase binding |
IPI
IPI: Inferred from physical interaction
|
18782775 | RGD |
| enables structural constituent of cytoskeleton |
IDA
IDA: Inferred from direct assay
|
16687515 | RGD |
| enables transmembrane transporter binding |
IPI
IPI: Inferred from physical interaction
|
19805355 | RGD |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| involved in nervous system development |
IEP
IEP: Inferred from expression pattern
|
9832159 | RGD |
| involved in paranodal junction assembly |
IEP
IEP: Inferred from expression pattern
|
16687515 | RGD |
| involved in response to methylmercury |
IEP
IEP: Inferred from expression pattern
|
12949909 | RGD |
EXP: Inferred from Experiment
IDA: Inferred from direct assay
IPI: Inferred from physical interaction
IMP: Inferred from mutant phenotype
IGI: Inferred from genetic interaction
IEP: Inferred from expression pattern
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
ankyrin-2 |
|
|
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Bioactive Molecules
(1)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS00700 | ANK2 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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