Celf1 - CUGBP, Elav-like family member 1 Gene

Also Known as Cugbp1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 362160

Summary

Enables mRNA 3'-UTR binding activity. Involved in mRNA destabilization and posttranscriptional gene silencing. Acts upstream of or within positive regulation of gene expression. Predicted to be located in cytoplasmic stress granule; nucleoplasm; and perinucleolar compartment. Predicted to be part of ribonucleoprotein complex. Predicted to be active in cytoplasm and nucleus. Orthologous to human CELF1 (CUGBP Elav-like family member 1). [provided by Alliance of Genome Resources, Apr 2022]

Celf1 Products (1)

mRNA Protein Name
NM_001025421.2 NP_001020592.1 CUGBP Elav-like family member 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables mRNA 3'-UTR binding IDA
IDA: Inferred from direct assay
30508596 RGD
Biological Process GO Annotation Evidence References Source
involved in cellular response to polyamine macromolecule IEP
IEP: Inferred from expression pattern
21737690 RGD
involved in mRNA destabilization IDA
IDA: Inferred from direct assay
30508596 RGD
acts upstream of negative regulation of cell population proliferation IDA
IDA: Inferred from direct assay
30514107 RGD
involved in negative regulation of epithelial cell proliferation IMP
IMP: Inferred from mutant phenotype
21737690 RGD
acts upstream of or within positive regulation of gene expression IDA
IDA: Inferred from direct assay
30514107 RGD
involved in post-transcriptional gene silencing IMP
IMP: Inferred from mutant phenotype
30508596 RGD
acts upstream of regulation of cell cycle IDA
IDA: Inferred from direct assay
30514107 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

CUGBP Elav-like family member 1

  • CELF-1

  • CUG triplet repeat RNA-binding protein 1

  • CUG-BP- and ETR-3-like factor 1

  • CUG-BP1

  • RNA-binding protein BRUNOL-2

  • bruno-like protein 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02459 CELF1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22429 Celf1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28952 Celf1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Celf1 NCBI NCBI:10658