Dusp15 - dual specificity phosphatase 15 Gene

Rattus norvegicus

Gene ID: 362238 | Gene type: protein coding

About Dusp15

Summary

Predicted to enable protein tyrosine Phosphatase activity and protein tyrosine/serine/threonine Phosphatase activity. Involved in negative regulation of transcription by RNA polymerase II and positive regulation of ERK1 and ERK2 cascade. Predicted to be located in plasma membrane. Predicted to be active in cytosol. Orthologous to human DUSP15 (dual specificity Phosphatase 15). [provided by Alliance of Genome Resources, Apr 2022]

Dusp15 Products(2)

mRNA	Protein	Name
NM_001108598.2	NP_001102068.2	dual specificity protein phosphatase 15 isoform 1
NM_001244784.1	NP_001231713.1	dual specificity protein phosphatase 15 isoform 2

Gene Ontology

Biological Process

Biological Process GO Annotation	Evidence	Reference	Source
involved in negative regulation of transcription by RNA polymerase II	IMP IMP: Inferred from mutant phenotype	27891578	RGD
involved in positive regulation of ERK1 and ERK2 cascade	IMP IMP: Inferred from mutant phenotype	27891578	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

dual specificity protein phosphatase 15

dual specificity phosphatase-like 15

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04056	DUSP15 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Dusp15	NCBI	NCBI:128853

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