Xpo5 - exportin 5 Gene

Predicted to enable several functions, including RISC complex binding activity; RNA binding activity; and nuclear export signal receptor activity. Predicted to contribute to pre-miRNA binding activity. Predicted to be involved in positive regulation of RNA interference and pre-miRNA export from nucleus. Predicted to act upstream of or within protein export from nucleus. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of RISC complex and RNA nuclear export complex. Predicted to be active in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in breast cancer; gastrointestinal system Cancer (multiple); lung carcinoma (multiple); multiple myeloma; and primary ovarian insufficiency. Orthologous to human XPO5 (exportin 5). [provided by Alliance of Genome Resources, Apr 2022]