2. Gene
  3. Dis3l2 - DIS3-like 3'-5' exoribonuclease 2 Gene

Dis3l2 - DIS3-like 3'-5' exoribonuclease 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as RGD1560168

Gene ID: 367307 | Gene type: protein coding

About Dis3l2

Summary

Predicted to enable 3'-5'-exoribonuclease activity; magnesium ion binding activity; and poly(U) RNA binding activity. Predicted to be involved in several processes, including RNA catabolic process; mitotic sister chromatid separation; and stem cell population maintenance. Predicted to be located in cytoplasm. Predicted to be part of exosome (RNase complex). Predicted to be active in P-body. Human ortholog(s) of this gene implicated in Perlman syndrome and nephroblastoma. Orthologous to human DIS3L2 (DIS3 like 3'-5' exoribonuclease 2). [provided by Alliance of Genome Resources, Apr 2022]

Dis3l2 Products(2)

mRNA Protein Name
NM_001109007.2 NP_001102477.2 DIS3-like exonuclease 2 isoform 1
NM_001172159.1 NP_001165630.1 DIS3-like exonuclease 2 isoform 2
Protein Preferred Names Protein Names

DIS3-like exonuclease 2

DIS3 mitotic control homolog-like 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03780 DIS3L2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-173081 4"-(2-(p-Chlorophenyl)acetoxyl)spiramycin Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dis3l2 NCBI NCBI:129563