Zfat - zinc finger and AT hook domain containing Gene

Also Known as Gm922; Zfat1; Zfp406

Species: Mus musculus

Gene Type: protein coding
Gene ID: 380993

Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific. Acts upstream of or within hematopoietic progenitor cell differentiation and spongiotrophoblast layer development. Predicted to be located in nucleus. Is expressed in several structures, including extraembryonic component; nervous system; and placenta. Human ortholog(s) of this gene implicated in autoimmune thyroiditis. Orthologous to human ZFAT (zinc finger and AT-hook domain containing). [provided by Alliance of Genome Resources, Apr 2022]

Zfat Products (3)

mRNA Protein Name
NM_001145888.2 NP_001139360.1 zinc finger protein ZFAT isoform 1
NM_001403039.1 NP_001389968.1 zinc finger protein ZFAT isoform 3
NM_198644.3 NP_941046.1 zinc finger protein ZFAT isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
20660741 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within hematopoietic progenitor cell differentiation IMP
IMP: Inferred from mutant phenotype
20660741 MGI
acts upstream of or within hemopoiesis IMP
IMP: Inferred from mutant phenotype
20660741 MGI
acts upstream of or within spongiotrophoblast layer development IMP
IMP: Inferred from mutant phenotype
20660741 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

zinc finger protein ZFAT

  • ZFAT zinc finger 1

  • zinc finger protein 403

  • zinc finger protein 406

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS16033 ZFAT Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Zfat NCBI NCBI:57623