1. Gene
  2. Zfat - zinc finger and AT hook domain containing Gene

Zfat - zinc finger and AT hook domain containing Gene

Mus musculus

Also known as Gm922; Zfat1; Zfp406

Gene ID: 380993 | Gene type: protein coding

About Zfat

Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific. Acts upstream of or within hematopoietic progenitor cell differentiation and spongiotrophoblast layer development. Predicted to be located in nucleus. Is expressed in several structures, including extraembryonic component; nervous system; and placenta. Human ortholog(s) of this gene implicated in autoimmune thyroiditis. Orthologous to human ZFAT (zinc finger and AT-hook domain containing). [provided by Alliance of Genome Resources, Apr 2022]

Zfat Products(3)

mRNA Protein Name
NM_001145888.2 NP_001139360.1 zinc finger protein ZFAT isoform 1
NM_001403039.1 NP_001389968.1 zinc finger protein ZFAT isoform 3
NM_198644.3 NP_941046.1 zinc finger protein ZFAT isoform 2
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
20660741 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within hematopoietic progenitor cell differentiation IMP
IMP: Inferred from mutant phenotype
20660741 MGI
acts upstream of or within hemopoiesis IMP
IMP: Inferred from mutant phenotype
20660741 MGI
acts upstream of or within spongiotrophoblast layer development IMP
IMP: Inferred from mutant phenotype
20660741 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

zinc finger protein ZFAT

ZFAT zinc finger 1

zinc finger protein 403

zinc finger protein 406

Orthologs Information

Species Symbol Source ID
Homo sapiens Zfat NCBI NCBI:57623