Slitrk3 - SLIT and NTRK-like family, member 3 Gene

Also Known as ST3

Species: Mus musculus

Gene Type: protein coding
Gene ID: 386750

Summary

Involved in regulation of presynapse assembly. Acts upstream of or within several processes, including GABAergic synaptic transmission; positive regulation of synapse assembly; and synapse organization. Located in GABA-ergic synapse and cell surface. Is integral component of postsynaptic membrane. Is expressed in alimentary system; bladder; central nervous system; neural retina; and peripheral nervous system. Orthologous to human SLITRK3 (SLIT and NTRK like family member 3). [provided by Alliance of Genome Resources, Apr 2022]

Slitrk3 Products (2)

mRNA Protein Name
NM_001357851.1 NP_001344780.1 SLIT and NTRK-like protein 3 precursor
NM_198864.3 NP_942564.2 SLIT and NTRK-like protein 3 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
29107521 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within axonogenesis IDA
IDA: Inferred from direct assay
14550773 MGI
acts upstream of or within gephyrin clustering involved in postsynaptic density assembly IGI
IGI: Inferred from genetic interaction
29107521 MGI
acts upstream of or within gephyrin clustering involved in postsynaptic density assembly IMP
IMP: Inferred from mutant phenotype
29107521 MGI
acts upstream of or within neurotransmitter-gated ion channel clustering IDA
IDA: Inferred from direct assay
29107521 MGI
acts upstream of or within neurotransmitter-gated ion channel clustering IGI
IGI: Inferred from genetic interaction
29107521 MGI
acts upstream of or within neurotransmitter-gated ion channel clustering IMP
IMP: Inferred from mutant phenotype
29107521 MGI
acts upstream of or within positive regulation of synapse assembly IDA
IDA: Inferred from direct assay
24613359 MGI
acts upstream of or within postsynaptic density assembly IMP
IMP: Inferred from mutant phenotype
29107521 MGI
involved in regulation of presynapse assembly IDA
IDA: Inferred from direct assay
22286174 MGI
involved in regulation of presynapse assembly IMP
IMP: Inferred from mutant phenotype
22286174 MGI
acts upstream of or within synaptic transmission, GABAergic IDA
IDA: Inferred from direct assay
29107521 MGI
acts upstream of or within synaptic transmission, GABAergic IGI
IGI: Inferred from genetic interaction
29107521 MGI
acts upstream of or within synaptic transmission, GABAergic IMP
IMP: Inferred from mutant phenotype
29107521 MGI
acts upstream of or within terminal button organization IMP
IMP: Inferred from mutant phenotype
29107521 MGI
Cellular Component GO Annotation Evidence References Source
is active in GABA-ergic synapse IDA
IDA: Inferred from direct assay
22286174 MGI
located in GABA-ergic synapse IDA
IDA: Inferred from direct assay
29107521 MGI
is active in GABA-ergic synapse IMP
IMP: Inferred from mutant phenotype
22286174 MGI
located in cell surface IDA
IDA: Inferred from direct assay
29107521 MGI
is active in postsynaptic membrane IDA
IDA: Inferred from direct assay
22286174 MGI
is active in postsynaptic membrane IMP
IMP: Inferred from mutant phenotype
22286174 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

SLIT and NTRK-like protein 3

  • slit and trk like gene 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13375 SLITRK3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slitrk3 NCBI NCBI:22865