2. Gene
  3. PDE5A - phosphodiesterase 5A Gene

PDE5A - phosphodiesterase 5A Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Sus scrofa

Also known as PDE5

Gene ID: 397616 | Gene type: protein coding

About PDE5A

Primary_assembly 8: 104,270,881-104,420,953 forward strand.Sscrofa11.1:CM000819.5

This gene has 2 transcripts (splice variants), 207 orthologues and 20 paralogues. Broad expression in lung (RPKM 22.2), ovary (RPKM 5.1) and 6 other tissues.

PDE5A Products(6)

mRNA Protein Name
XM_021101648.1 XP_020957307.1 cGMP-specific 3',5'-cyclic phosphodiesterase isoform X1
XM_021101652.1 XP_020957311.1 cGMP-specific 3',5'-cyclic phosphodiesterase isoform X4
XM_021101654.1 XP_020957313.1 cGMP-specific 3',5'-cyclic phosphodiesterase isoform X6
XM_021101653.1 XP_020957312.1 cGMP-specific 3',5'-cyclic phosphodiesterase isoform X5
XM_021101650.1 XP_020957309.1 cGMP-specific 3',5'-cyclic phosphodiesterase isoform X3
XM_021101649.1 XP_020957308.1 cGMP-specific 3',5'-cyclic phosphodiesterase isoform X2

PDE5A Protein Structure

GAF

GAF: smart00065 (153 - 310)

GAF

GAF: smart00065 (336 - 502)

PDEase_I

PDEase_I: pfam00233 (652 - 886)

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  • 916 a.a.
Protein Preferred Names Protein Names

cGMP-specific 3',5'-cyclic phosphodiesterase

cGMP-dependent 3',5'-cyclic phosphodiesterase 5A

phosphodiesterase isozyme 5

Related Agents

Clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-112831 Osoresnontrine Inhibitor 99.94% Phase 2
HY-170435 PDE5-IN-13 Inhibitor / Phase 1
Pre-clinical Phase
Bioactive Molecules (8)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-106230A Dasantafil Inhibitor 98.35% Unkown
HY-N1343 Robustine Inhibitor 99.70% Unkown
HY-103084 PDE5-IN-1 Inhibitor / Unkown
HY-161851 MDL3 Inhibitor / Unkown
HY-N17363 Confusameline / Unkown
HY-RS10227 PDE5A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS10228 Pde5a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS10229 Pde5a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens PDE5A NCBI NCBI:8654
Mus musculus PDE5A NCBI NCBI:242202