SIRT6 - sirtuin 6 Gene
Species: Canis lupus familiaris (sub-species: familiaris)
Gene Type: protein coding
Gene ID: 485045
About SIRT6
Primary_assembly 20: 56,072,611-56,083,837 forward strand.ROS_Cfam_1.0:CM025119.1
This gene has 3 transcripts (splice variants), 193 orthologues and 6 paralogues.
SIRT6 Products (11)
| mRNA | Protein | Name |
|---|---|---|
| XM_038429088.1 | XP_038285016.1 | NAD-dependent protein deacetylase sirtuin-6 isoform X4 |
| XM_038429084.1 | XP_038285012.1 | NAD-dependent protein deacetylase sirtuin-6 isoform X4 |
| XM_038429090.1 | XP_038285018.1 | NAD-dependent protein deacetylase sirtuin-6 isoform X5 |
| XM_038429091.1 | XP_038285019.1 | NAD-dependent protein deacetylase sirtuin-6 isoform X5 |
| XM_038429089.1 | XP_038285017.1 | NAD-dependent protein deacetylase sirtuin-6 isoform X4 |
| XM_038429082.1 | XP_038285010.1 | NAD-dependent protein deacetylase sirtuin-6 isoform X3 |
| XM_038429085.1 | XP_038285013.1 | NAD-dependent protein deacetylase sirtuin-6 isoform X4 |
| XM_038429080.1 | XP_038285008.1 | NAD-dependent protein deacetylase sirtuin-6 isoform X1 |
| XM_038429087.1 | XP_038285015.1 | NAD-dependent protein deacetylase sirtuin-6 isoform X4 |
| XM_038429083.1 | XP_038285011.1 | NAD-dependent protein deacetylase sirtuin-6 isoform X4 |
| XM_038429081.1 | XP_038285009.1 | NAD-dependent protein deacetylase sirtuin-6 isoform X2 |
SIRT6 Protein Structure
SIRT7
SIRT7: cd01410 (64 - 274)
- 0
- 100
- 200
- 300
- 377 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
NAD-dependent deacetylase sirtuin-6 NAD-dependent protein deacetylase sirtuin-6 |
|
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
Bioactive Molecules
(17)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-107454 | OSS_128167 | Inhibitor | 98.92% | Unkown |
| HY-115453 | UBCS039 | Activator | 98.88% | Unkown |
| HY-N0010 | Geniposidic acid | Agonist | 98.87% | Unkown |
| HY-119376 | MDL-800 | Activator | 99.11% | Unkown |
| HY-148712 | SIRT6 activator 12q | Activator | 99.83% | Unkown |
| HY-103721 | SIRT6-IN-2 | Inhibitor | 99.92% | Unkown |
| HY-16605 | SIRT6-IN-6 | Inhibitor | 98.59% | Unkown |
| HY-156757 | MDL-811 | Activator | 99.68% | Unkown |
| HY-156027 | SIRT6-IN-3 | Inhibitor | 98.19% | Unkown |
| HY-150727 | SIRT5 inhibitor 4 | Inhibitor | 98.37% | Unkown |
| HY-P3364A | Ac-QPKK(Ac)-AMC acetate | Substrate | 99.38% | Unkown |
| HY-153104 | CrBKA | 98.46% | Unkown | |
| HY-178990 | SIRT6-IN-5 | Inhibitor | / | Unkown |
| HY-170402 | SIRT6-IN-4 | Inhibitor | / | Unkown |
| HY-177878 | IMU-856 | Modulator | / | Unkown |
| HY-182061 | SIRT6 activator 3 | Activator | / | Unkown |
| HY-169159 | SIRT6 activator 2 | Activator | / | Unkown |
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