2. Gene
  3. SIRT6 - sirtuin 6 Gene

SIRT6 - sirtuin 6 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Canis lupus familiaris (sub-species: familiaris)
Gene ID: 485045 | Gene type: protein coding

About SIRT6

Primary_assembly 20: 56,072,611-56,083,837 forward strand.ROS_Cfam_1.0:CM025119.1

This gene has 3 transcripts (splice variants), 193 orthologues and 6 paralogues.

SIRT6 Products(11)

mRNA Protein Name
XM_038429088.1 XP_038285016.1 NAD-dependent protein deacetylase sirtuin-6 isoform X4
XM_038429084.1 XP_038285012.1 NAD-dependent protein deacetylase sirtuin-6 isoform X4
XM_038429090.1 XP_038285018.1 NAD-dependent protein deacetylase sirtuin-6 isoform X5
XM_038429091.1 XP_038285019.1 NAD-dependent protein deacetylase sirtuin-6 isoform X5
XM_038429089.1 XP_038285017.1 NAD-dependent protein deacetylase sirtuin-6 isoform X4
XM_038429082.1 XP_038285010.1 NAD-dependent protein deacetylase sirtuin-6 isoform X3
XM_038429085.1 XP_038285013.1 NAD-dependent protein deacetylase sirtuin-6 isoform X4
XM_038429080.1 XP_038285008.1 NAD-dependent protein deacetylase sirtuin-6 isoform X1
XM_038429087.1 XP_038285015.1 NAD-dependent protein deacetylase sirtuin-6 isoform X4
XM_038429083.1 XP_038285011.1 NAD-dependent protein deacetylase sirtuin-6 isoform X4
XM_038429081.1 XP_038285009.1 NAD-dependent protein deacetylase sirtuin-6 isoform X2

SIRT6 Protein Structure

SIRT7

SIRT7: cd01410 (64 - 274)

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  • 300
  • 377 a.a.
Protein Preferred Names Protein Names

NAD-dependent deacetylase sirtuin-6

NAD-dependent protein deacetylase sirtuin-6

Related Agents

Pre-clinical Phase
Bioactive Molecules (17)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-107454 OSS_128167 Inhibitor 98.92% Unkown
HY-115453 UBCS039 Activator 98.88% Unkown
HY-N0010 Geniposidic acid Agonist 98.87% Unkown
HY-119376 MDL-800 Activator 99.11% Unkown
HY-148712 SIRT6 activator 12q Activator 99.83% Unkown
HY-103721 SIRT6-IN-2 Inhibitor 99.92% Unkown
HY-156757 MDL-811 Activator 99.68% Unkown
HY-16605 SIRT6-IN-6 Inhibitor 98.59% Unkown
HY-156027 SIRT6-IN-3 Inhibitor 98.19% Unkown
HY-P3364A Ac-QPKK(Ac)-AMC acetate Substrate / Unkown
HY-153104 CrBKA 98.46% Unkown
HY-150727 SIRT5 inhibitor 4 Inhibitor 98.37% Unkown
HY-178990 SIRT6-IN-5 Inhibitor / Unkown
HY-170402 SIRT6-IN-4 Inhibitor / Unkown
HY-177878 IMU-856 Modulator / Unkown
HY-182061 SIRT6 activator 3 Activator / Unkown
HY-169159 SIRT6 activator 2 Activator / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens SIRT6 NCBI NCBI:51548