CrBKA
Based on 1 Customer Validation
CrBKA is a fluorogenic small-molecule substrate of SIRT6 with weak activity.
For research use only. We do not sell to patients.
- Purity: 98.46%
- CAS No.: 2260810-48-6
- Formula: C28H31N3O6
- Molecular Weight:505.56
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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SIRT6 |
Chemical Information
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CAS No. 2260810-48-6
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Appearance Solid
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Molecular Weight 505.56
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Formula C28H31N3O6
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Color White to off-white
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SMILES
CC(C1=CC=C(NC([C@H](CCCCNC(/C=C/C)=O)NC(OCC2=CC=CC=C2)=O)=O)C=C1O3)=CC3=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : ≥ 100 mg/mL (197.80 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.9780 mL | 9.8900 mL | 19.7800 mL | 49.4501 mL |
| 5 mM | 0.3956 mL | 1.9780 mL | 3.9560 mL | 9.8900 mL | |
| 10 mM | 0.1978 mL | 0.9890 mL | 1.9780 mL | 4.9450 mL | |
| 15 mM | 0.1319 mL | 0.6593 mL | 1.3187 mL | 3.2967 mL | |
| 20 mM | 0.0989 mL | 0.4945 mL | 0.9890 mL | 2.4725 mL | |
| 25 mM | 0.0791 mL | 0.3956 mL | 0.7912 mL | 1.9780 mL | |
| 30 mM | 0.0659 mL | 0.3297 mL | 0.6593 mL | 1.6483 mL | |
| 40 mM | 0.0495 mL | 0.2473 mL | 0.4945 mL | 1.2363 mL | |
| 50 mM | 0.0396 mL | 0.1978 mL | 0.3956 mL | 0.9890 mL | |
| 60 mM | 0.0330 mL | 0.1648 mL | 0.3297 mL | 0.8242 mL | |
| 80 mM | 0.0247 mL | 0.1236 mL | 0.2473 mL | 0.6181 mL | |
| 100 mM | 0.0198 mL | 0.0989 mL | 0.1978 mL | 0.4945 mL |
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