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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
14 Results for "
55421
" in MedChemExpress (MCE) Product Catalog:
Products (14)
14 Results for "55421" in MCE Product Catalog:
11
Category:
Polysaccharides Microorganisms Anti-aging Metabolic Disease Disease Research Fields Saccharides
Target:
4
Target:
Research Areas:
CYM-5541 (ML249) is an selective and allosteric S1P3 receptor agonist with an EC50 between 72 and 132 nM.
Synonyms: CGP52421
3-Hydroxy Midostaurin (CGP 52421), a metabolite of PKC412, effectively inhibits FMS-like tyrosine kinase-3 (FLT3) autophosphorylation with IC50s of approximately 132 nM and 9.8 μM in culture medium and plasma, respectively. 3-Hydroxy Midostaurin is less selective but more cytotoxic than PKC412 .
Cat. No.: HY-B0089R
CAS No.: 56180-94-0
Synonyms: BAY g 5421 (Standard)
Category:
Target:
Cat. No.: HY-108263B
CAS No.: 155848-20-7
Synonyms: (R)-CGP52421
Target:
Research Areas:
(R)-3-Hydroxy Midostaurin ((R)-CGP52421) is a potent kinases inhibitor. (R)-3-Hydroxy Midostaurin is a major metabolite of midostaurin (PKC412; HY-10230) undergoing by the hepatic CYP3A4 enzyme. (R)-3-Hydroxy Midostaurin has the potential for acute myeloid leukemia (AML) .
Cat. No.: HY-B0089A
CAS No.: 1221158-13-9
Synonyms: Bay-g 5421 sulfate
Target:
Cat. No.: HY-108263A
CAS No.: 945260-14-0
Synonyms: (S)-CGP52421
Target:
Research Areas:
(S)-3-Hydroxy Midostaurin ((S)-CGP52421) is a potent kinases inhibitor with IC50 values of <400 nM for 13 kinases (VEGFR-2, TRK-A, FLT3, et). (S)-3-Hydroxy Midostaurin is a minor metabolite of midostaurin (PKC412; HY-10230) undergoing by the hepatic CYP3A4 enzyme. (S)-3-Hydroxy Midostaurin has the potential for acute myeloid leukemia (AML) .
Cat. No.: HY-108263S
Synonyms: CGP52421-d5
Cat. No.: HY-B0089S
CAS No.: 1260619-60-0
Synonyms: BAY g 5421-d4
Cat. No.: HY-W751180
Synonyms: CGP52421-13C6
Cat. No.: HY-P85829
Synonyms: B cell Oct binding protein 1; B cell specific coactivator OBF 1; B cell specific coactivator OBF1; B-cell-specific coactivator OBF-1; BOB 1; BOB-1; OBF 1; OBF1; OBF1_HUMAN; OCA B; OCA-B; OCAB; OCT binding factor 1; OCT-binding factor 1; POU class 2 associating factor 1; POU domain class 2 associating factor 1; POU domain class 2-associating factor 1; Pou2af1
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
