CMAS - cytidine monophosphate N-acetylneuraminic acid synthetase Gene

Homo sapiens

Also known as CSS

Gene ID: 55907 | Gene type: protein coding

About CMAS

Cytogenetic location: 12p12.1 Genomic coordinates (GRCh38): 12:22,046,218-22,065,668 (from NCBI)

This gene has 5 transcripts (splice variants) and 249 orthologues. Ubiquitous expression in testis (RPKM 46.2), colon (RPKM 38.5) and 25 other tissues.

Summary

This gene encodes an Enzyme that converts N-acetylneuraminic acid (NeuNAc) to cytidine 5'-monophosphate N-acetylneuraminic acid (CMP-NeuNAc). This process is important in the formation of sialylated glycoprotein and glycolipids. This modification plays a role in cell-cell communications and immune responses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]

CMAS Products(1)

mRNA	Protein	Name
NM_018686.6	NP_061156.1	N-acylneuraminate cytidylyltransferase

CMAS Protein Structure

CTP_transf_3

0
100
200
300
400
434 a.a.

Protein Preferred Names

Protein Names

N-acylneuraminate cytidylyltransferase

CMP-N-acetylneuraminic acid synthase

Related Diseases

Diseases

Alias

Palmoplantar Keratoderma And Congenital Alopecia 2

Cataract-Alopecia-Sclerodactyly Syndrome	Cass
Autosomal Recessive Palmoplantar Keratoderma And Congenital Alopecia	PPKCA2
Autosomal Recessive Palmoplantar Hyperkeratosis And Congenital Alopecia	Palmoplantar Keratoderma And Congenital Alopecia, Wallis Type
Ppk-Ca, Wallis Type	Cataract, Alopecia, Sclerodactyly
Ppkca, Wallis Type	Ppkca Wallis Type
Cataract, Alopecia, Sclerodactyly Syndrome

Coffin-Siris Syndrome 2

CSS2	Mrd14
Mental Retardation, Autosomal Dominant 14	Autosomal Dominant Mental Retardation 14
Coffin-Siris Syndrome, Type 2

Coffin-Siris Syndrome 4

CSS4	Mrd16
Mental Retardation, Autosomal Dominant 16	Autosomal Dominant Mental Retardation 16
Coffin-Siris Syndrome, Type 4

Brooke-Spiegler Syndrome

Cyld Cutaneous Syndrome	Spiegler-Brooke Syndrome
Familial Cylindromatosis	BRSS
Bss	Sbs
Multiple Familial Trichoepithelioma	Ancell-Spiegler Cylindromas
Familial Multiple Trichoepithelioma	Trichoepithelioma
Fc	Mft
Multiple Familial Trichoepitheliomas	Ccs
Turban Tumor Syndrome	Schilbach-Rott Syndrome
Eccrine Dermal Cylindroma	Familial Multiple Trichoepitheliomata

Parotid Disease

Parotid Diseases

Siderosis

Pulmonary Siderosis	Deposition Of Iron
Arc-Welders' Disease	Arc-Welders' Lung
Arc-Welders' Nodulation	Arc-Welders' Pneumoconiosis
Iron Oxide Lung	Iron Pneumoconiosis
Pneumoconiosis Siderotico	Siderotic Lung Disease
Steel Grinders' Disease	Welders' Lung
Welders' Siderosis	Lung Fibrosis With Siderosis

Hemosiderosis

Haemosiderosis

Iron Overload

Parotitis

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (9)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-134923	CA77.1	Inducer	99.98%	Unkown
HY-101106	AR7	Antagonist	98.85%	Unkown
HY-112483	QX77	Activator	99.59%	Unkown
HY-112486	TA-316		98.19%	Unkown
HY-155747	FDW028	Inhibitor	99.51%	Unkown
HY-158225	Methacrylated Type I collagen		/	Unkown
HY-RS02853	CMA1 Human Pre-designed siRNA Set A		/	Unkown
HY-RS02854	CMAS Human Pre-designed siRNA Set A		/	Unkown
HY-P1098B	Ac2-26 ammonium	Degrader	97.22%	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	CMAS	VGNC	VGNC:60993
Rattus norvegicus	CMAS	RGD	RGD:1310911
Mus musculus	CMAS	MGD	MGI:1337124
Macaca mulatta	CMAS	VGNC	VGNC:71201
Canis familiaris	CMAS	VGNC	VGNC:39375
Bos taurus	CMAS	VGNC	VGNC:27476

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