Pes1 - pescadillo ribosomal biogenesis factor 1 Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 64934

Summary

Predicted to enable RNA binding activity. Acts upstream of or within maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); nucleolus organization; and protein localization to organelle. Located in condensed chromosome and nucleolus. Part of PeBoW complex. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and skeletal muscle. Orthologous to human PES1 (pescadillo ribosomal biogenesis factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Pes1 Products (1)

mRNA Protein Name
NM_022889.3 NP_075027.1 pescadillo homolog

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
15225545 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IMP
IMP: Inferred from mutant phenotype
25190460 MGI
acts upstream of or within nucleolus organization IMP
IMP: Inferred from mutant phenotype
12237316 MGI
acts upstream of or within protein localization to organelle IMP
IMP: Inferred from mutant phenotype
15225545 MGI
acts upstream of or within rRNA processing IGI
IGI: Inferred from genetic interaction
15225545 MGI
acts upstream of or within rRNA processing IMP
IMP: Inferred from mutant phenotype
15225545 MGI
acts upstream of or within ribosome biogenesis IMP
IMP: Inferred from mutant phenotype
12237316 MGI
Cellular Component GO Annotation Evidence References Source
part of PeBoW complex IDA
IDA: Inferred from direct assay
16738141 MGI
located in condensed chromosome IDA
IDA: Inferred from direct assay
12237316 MGI
located in nucleolus IDA
IDA: Inferred from direct assay
12237316 MGI
located in nucleus IDA
IDA: Inferred from direct assay
11112348 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

pescadillo homolog

  • pescadillo homolog 1, containing BRCT domain

Related Agents

  • Approval
  • Pre-clinical Phase

Approval

Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B0304A Dapoxetine hydrochloride Inhibitor 99.96% Unkown
HY-B0304 Dapoxetine Inhibitor / Unkown

Pre-clinical Phase

Bioactive Molecules (18)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-120991 1-Palmitoyl-2-linoleoyl-sn-glycero-3-PE 98.0% Unkown
HY-157697 1-1(Z)-Octadecenyl-2-arachidonoyl-sn-glycero-3-PE ≥99.0% Unkown
HY-143671S 1-Stearoyl-2-arachidonoyl-sn-glycero-3-PE-d11 99.0% Unkown
HY-P1695 Cinnamycin Inhibitor 98.4% Unkown
HY-141617S 1-Palmitoyl-d9-2-hydroxy-sn-glycero-3-PE / Unkown
HY-165116 1-1(Z)-Octadecenyl-2-docosahexaenoyl-sn-glycero-3-PE / Unkown
HY-170021 Dapoxetine-d7 Inhibitor / Unkown
HY-170459 18:1-12:0 Biotin PE / Unkown
HY-P5809 Pe1b Inhibitor / Unkown
HY-RS10336 PES1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS11392 PTGS1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W583868S 1-Palmitoyl-2-oleoyl-sn-glycero-3-PE-d62 / Unkown
HY-145473S 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE-d11 / Unkown
HY-158750 1-1(Z)-Octadecenyl-2-adrenoyl-sn-glycero-3-pe / Unkown
HY-158947 1-1(Z)-Hexadecenyl-2-palmitoyl-sn-glycero-3-PE / Unkown
HY-158947S 1-1(Z)-Hexadecenyl-2-Palmitoyl-d9-sn-glycero-3-PE / Unkown
HY-167894 DA-8031 Inhibitor / Unkown
HY-W290532 (Rac)-Dapoxetine hydrochloride Inhibitor 99.49% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pes1 NCBI NCBI:23481