2. Gene
  3. Pes1 - pescadillo ribosomal biogenesis factor 1 Gene

Pes1 - pescadillo ribosomal biogenesis factor 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus
Gene ID: 64934 | Gene type: protein coding

About Pes1

Summary

Predicted to enable RNA binding activity. Acts upstream of or within maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); nucleolus organization; and protein localization to organelle. Located in condensed chromosome and nucleolus. Part of PeBoW complex. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and skeletal muscle. Orthologous to human PES1 (pescadillo ribosomal biogenesis factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Pes1 Products(1)

mRNA Protein Name
NM_022889.3 NP_075027.1 pescadillo homolog
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
15225545 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IMP
IMP: Inferred from mutant phenotype
25190460 MGI
acts upstream of or within nucleolus organization IMP
IMP: Inferred from mutant phenotype
12237316 MGI
acts upstream of or within protein localization to organelle IMP
IMP: Inferred from mutant phenotype
15225545 MGI
acts upstream of or within rRNA processing IGI
IGI: Inferred from genetic interaction
15225545 MGI
acts upstream of or within rRNA processing IMP
IMP: Inferred from mutant phenotype
15225545 MGI
acts upstream of or within ribosome biogenesis IMP
IMP: Inferred from mutant phenotype
12237316 MGI
Cellular Component GO Annotation Evidence Reference Source
part of PeBoW complex IDA
IDA: Inferred from direct assay
16738141 MGI
located in condensed chromosome IDA
IDA: Inferred from direct assay
12237316 MGI
located in nucleolus IDA
IDA: Inferred from direct assay
12237316 MGI
located in nucleus IDA
IDA: Inferred from direct assay
11112348 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

pescadillo homolog

pescadillo homolog 1, containing BRCT domain

Related Agents

Approval
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B0304A Dapoxetine hydrochloride Inhibitor 99.96% Unkown
HY-B0304 Dapoxetine Inhibitor / Unkown
Pre-clinical Phase
Bioactive Molecules (18)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-120991 1-Palmitoyl-2-linoleoyl-sn-glycero-3-PE 98.0% Unkown
HY-157697 1-1(Z)-Octadecenyl-2-arachidonoyl-sn-glycero-3-PE ≥99.0% Unkown
HY-143671S 1-Stearoyl-2-arachidonoyl-sn-glycero-3-PE-d11 99.0% Unkown
HY-P1695 Cinnamycin Inhibitor 98.4% Unkown
HY-141617S 1-Palmitoyl-d9-2-hydroxy-sn-glycero-3-PE / Unkown
HY-165116 1-1(Z)-Octadecenyl-2-docosahexaenoyl-sn-glycero-3-PE / Unkown
HY-170021 Dapoxetine-d7 Inhibitor / Unkown
HY-170459 18:1-12:0 Biotin PE / Unkown
HY-P5809 Pe1b Inhibitor / Unkown
HY-RS10336 PES1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS11392 PTGS1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W583868S 1-Palmitoyl-2-oleoyl-sn-glycero-3-PE-d62 / Unkown
HY-145473S 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE-d11 / Unkown
HY-158750 1-1(Z)-Octadecenyl-2-adrenoyl-sn-glycero-3-pe / Unkown
HY-158947 1-1(Z)-Hexadecenyl-2-palmitoyl-sn-glycero-3-PE / Unkown
HY-158947S 1-1(Z)-Hexadecenyl-2-Palmitoyl-d9-sn-glycero-3-PE / Unkown
HY-167894 DA-8031 Inhibitor / Unkown
HY-W290532 (Rac)-Dapoxetine hydrochloride Inhibitor 99.49% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pes1 NCBI NCBI:23481