2. Membrane Transporter/Ion Channel
  3. Sodium Channel
  4. Pe1b

Pe1b (μ-TrTx-Pe1b) is a selective Nav1.7 inhibitor with an IC50 of 167 nM.

For research use only. We do not sell to patients.

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Pe1b Chemical Structure

Pe1b Chemical Structure

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Pe1b Related Antibodies

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Description

Pe1b (μ-TrTx-Pe1b) is a selective Nav1.7 inhibitor with an IC50 of 167 nM[1].

IC50 & Target

IC50: 167 nM (Nav1.7), 696 nM (Nav1.6), 3.49 μM (Nav1.2), ＞10 μM (Nav1.5)[1]
Molecular Weight

3975.43

Formula

C175H237N47O49S6
Sequence

Glu-Cys-Arg-Tyr-Trp-Leu-Gly-Gly-Cys-Ser-Lys-Thr-Gly-Asp-Cys-Cys-Glu-His-Leu-Ser-Cys-Ser-Pro-Lys-Trp-His-Trp-Cys-Val-Trp-Asp-Gly-Thr-Phe (Disulfide bridge: Cys2-Cys16,Cys9-Cys21,Cys15-Cys28)
Sequence Shortening

ECRYWLGGCSKTGDCCEHLSCSPKWHWCVWDGTF (Disulfide bridge: Cys2-Cys16,Cys9-Cys21,Cys15-Cys28)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Pe1b Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pe1bμ-TrTx-Pe1bSodium ChannelNa channelsNa+ channelsPhormingochilus everettiXenopus oocytesanalgesicInhibitorinhibitorinhibit

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HY-P5809
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