Pmepa1 - prostate transmembrane protein, androgen induced 1 Gene

Also Known as Stag1; Erg1.2; N4wbp4; Tmepai; 2210418I02Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 65112

Summary

Predicted to enable R-SMAD binding activity and WW domain binding activity. Involved in negative regulation of pathway-restricted SMAD protein phosphorylation and negative regulation of transforming growth factor beta receptor signaling pathway. Predicted to be located in endosome membrane. Predicted to be active in Golgi membrane and early endosome membrane. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and integumental system. Orthologous to human PMEPA1 (prostate transmembrane protein, androgen induced 1). [provided by Alliance of Genome Resources, Apr 2022]

Pmepa1 Products (3)

mRNA Protein Name
NM_001413585.1 NP_001400514.1 protein TMEPAI isoform 3 precursor
NM_001413590.1 NP_001400519.1 protein TMEPAI isoform 1
NM_022995.4 NP_075371.2 protein TMEPAI isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
11042109 MGI
Biological Process GO Annotation Evidence References Source
involved in negative regulation of SMAD protein signal transduction IDA
IDA: Inferred from direct assay
20129061 MGI
involved in negative regulation of transforming growth factor beta receptor signaling pathway IDA
IDA: Inferred from direct assay
20129061 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein TMEPAI

  • NEDD4 WW domain-binding protein 4

  • Nedd4 WW binding protein 4

  • transmembrane prostate androgen-induced protein

  • transmembrane, prostate androgen induced RNA

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-179123 ZC9 / Unkown
HY-RS10761 PMEPA1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pmepa1 NCBI NCBI:56937