Nup62 - nucleoporin 62 Gene

Rattus norvegicus

Also known as Np62

Gene ID: 65274 | Gene type: protein coding

About Nup62

Summary

Enables Kinesin binding activity. A structural constituent of nuclear pore. Involved in several processes, including protein import into nucleus; regulation of protein import into nucleus; and spermatogenesis. Located in annulate lamellae and nuclear membrane. Part of nuclear pore. Human ortholog(s) of this gene implicated in primary biliary cholangitis and striatonigral degeneration. Orthologous to human NUP62 (nucleoporin 62). [provided by Alliance of Genome Resources, Apr 2022]

Nup62 Products(1)

mRNA	Protein	Name
NM_023098.2	NP_075586.1	nuclear pore glycoprotein p62

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables kinesin binding	IPI IPI: Inferred from physical interaction	16371587	RGD
enables protein binding	IPI IPI: Inferred from physical interaction	8707840	RGD
enables protein-containing complex binding	IPI IPI: Inferred from physical interaction	22036567	RGD
enables structural constituent of nuclear pore	IDA IDA: Inferred from direct assay	8589458	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in protein import into nucleus	IMP IMP: Inferred from mutant phenotype	11266456	RGD
involved in regulation of protein import into nucleus	IDA IDA: Inferred from direct assay	8707840	RGD
involved in spermatogenesis	IEP IEP: Inferred from expression pattern	16371587	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in annulate lamellae	IDA IDA: Inferred from direct assay	8832404	RGD
located in nuclear membrane	IDA IDA: Inferred from direct assay	16371587	RGD
part of nuclear pore	IDA IDA: Inferred from direct assay	8589458	RGD
part of protein-containing complex	IDA IDA: Inferred from direct assay	24574455	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

nuclear pore glycoprotein p62

62 kDa nucleoporin	nuclear pore glycoprotein 62
nucleoporin Nup62

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-W039939	2-Azido-2-deoxy-D-glucose, 98%	Substrate	98.0%	Unkown
HY-RS09697	NUP62 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Nup62	NCBI	NCBI:23636

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