Trappc2 - trafficking protein particle complex 2 Gene

Also Known as Sedl; TRS20; MIP-2A; 1110066L09Rik; 1810064C02Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 66226

Summary

Predicted to enable transmembrane transporter binding activity. Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport; regulation of transcription, DNA-templated; and skeletal system development. Part of TRAPP complex. Is expressed in several structures, including eye; genitourinary system; gut; hemolymphoid system; and nervous system. Human ortholog(s) of this gene implicated in X-linked spondyloepiphyseal dysplasia tarda. Orthologous to human TRAPPC2 (trafficking protein particle complex subunit 2). [provided by Alliance of Genome Resources, Apr 2022]

Trappc2 Products (2)

mRNA Protein Name
NM_001313722.1 NP_001300651.1 trafficking protein particle complex subunit 2 isoform 2
NM_025432.4 NP_079708.2 trafficking protein particle complex subunit 2 isoform 1

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
17027922 MGI
Cellular Component GO Annotation Evidence References Source
part of TRAPP complex IDA
IDA: Inferred from direct assay
17027922 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

trafficking protein particle complex subunit 2

  • sedlin

  • spondyloepiphyseal dysplasia tarda protein

  • spondyloepiphyseal dysplasia, late

Trappc2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Cross
Trappc2 Q9CQP2 TRAPPC9 Homo sapiens Q96Q05
Anti Tag CoIP
21858081
Intra
Trappc2 Q9CQP2 Spata4 Mus musculus Q8K3V1
Anti Bait CoIP
21827752
Intra
Trappc2 Q9CQP2 Spata4 Mus musculus Q8K3V1
Pull Down
21827752
Intra
Trappc2 Q9CQP2 Spata4 Mus musculus Q8K3V1
GMS
21827752
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14988 TRAPPC2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14989 TRAPPC2L Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Trappc2 NCBI NCBI:6399