Itgb3bp - integrin beta 3 binding protein (beta3-endonexin) Gene

Also Known as CENP-R; 4930471O16Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 67733

Summary

Predicted to be involved in CENP-A containing chromatin assembly and regulation of transcription, DNA-templated. Predicted to act upstream of or within apoptotic process and cell division. Predicted to be located in kinetochore and nucleus. Predicted to be active in nucleoplasm. Is expressed in brain; ovary; seminiferous tubule; spermatocyte; and spermatogonium. Orthologous to human ITGB3BP (Integrin subunit beta 3 binding protein). [provided by Alliance of Genome Resources, Apr 2022]

Itgb3bp Products (4)

mRNA Protein Name
NM_001362974.1 NP_001349903.1 centromere protein R isoform 2
NM_001362975.1 NP_001349904.1 centromere protein R isoform 3
NM_001362976.1 NP_001349905.1 centromere protein R isoform 4
NM_026348.4 NP_080624.1 centromere protein R isoform 1

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within negative regulation of epithelial cell apoptotic process IMP
IMP: Inferred from mutant phenotype
28795467 MGI
acts upstream of or within positive regulation of epithelial cell proliferation IMP
IMP: Inferred from mutant phenotype
28795467 MGI
Cellular Component GO Annotation Evidence References Source
located in kinetochore IDA
IDA: Inferred from direct assay
28795467 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

centromere protein R

  • nuclear receptor-interacting factor 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06967 ITGB3BP Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Itgb3bp NCBI NCBI:23421