Nkx6-3 - NK6 homeobox 3 Gene

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription repressor activity, RNA polymerase II-specific; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell differentiation; negative regulation of transcription by RNA polymerase II; and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within cell fate determination; glandular epithelial cell differentiation; and negative regulation of epithelial cell differentiation. Predicted to be active in nucleus. Orthologous to human NKX6-3 (NK6 homeobox 3). [provided by Alliance of Genome Resources, Apr 2022]