Mrln - myoregulin Gene

Also Known as Mln; Linc-RAM; 2310015B20Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 69563

Summary

This gene encodes a small peptide that shares structural similarity to the small peptides sarcolipin and phospholamban, which are key regulators of sarcoplasmic reticulum CA(2+)-ATPases (SERCAs). This protein is thought to have a similar function to these peptides, regulating CA(2+) reuptake in the sarcoplasmic reticulum by inhibiting the CA(2+) pump activity of SERCAs. [provided by RefSeq, Feb 2015]

Mrln Products (1)

mRNA Protein Name
NM_001304739.1 NP_001291668.1 myoregulin

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables enzyme inhibitor activity IDA
IDA: Inferred from direct assay
25640239 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
25640239 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of calcium ion import into sarcoplasmic reticulum IMP
IMP: Inferred from mutant phenotype
25640239 MGI
acts upstream of or within negative regulation of ATPase-coupled calcium transmembrane transporter activity IDA
IDA: Inferred from direct assay
27923914 MGI
acts upstream of or within negative regulation of calcium ion binding IDA
IDA: Inferred from direct assay
27923914 MGI
acts upstream of or within negative regulation of calcium ion import into sarcoplasmic reticulum IDA
IDA: Inferred from direct assay
25640239 MGI
acts upstream of or within negative regulation of calcium ion import into sarcoplasmic reticulum IMP
IMP: Inferred from mutant phenotype
25640239 MGI
acts upstream of or within response to wounding IEP
IEP: Inferred from expression pattern
24917243 MGI
Cellular Component GO Annotation Evidence References Source
located in endoplasmic reticulum membrane IDA
IDA: Inferred from direct assay
27923914 MGI
located in sarcoplasmic reticulum membrane IDA
IDA: Inferred from direct assay
25640239 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

myoregulin

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08654 MRLN Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mrln NCBI NCBI:100507027