MRLN - myoregulin Gene

Also Known as M1; MLN; MUSER1; Linc-RAM; LINC00948

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 100507027

About MRLN

Cytogenetic location: 10q21.2 Genomic coordinates (GRCh38): 10:59,736,692-59,753,455 (from NCBI)

This gene has 11 transcripts (splice variants) and 22 orthologues. Biased expression in kidney (RPKM 2.5), prostate (RPKM 1.2) and 3 other tissues.

Summary

This gene encodes a small peptide that shares structural similarity to the small peptides sarcolipin and phospholamban, which are key regulators of sarcoplasmic reticulum CA(2+)-ATPases (SERCAs). This protein is thought to have a similar function to these peptides, regulating CA(2+) reuptake in the sarcoplasmic reticulum by inhibiting the CA(2+) pump activity of SERCAs. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2015]

MRLN Products (2)

mRNA Protein Name
NM_001304731.2 NP_001291660.1 myoregulin
NM_001304732.2 NP_001291661.1 myoregulin
Protein Preferred Names Protein Names

myoregulin

  • Linc-RNA activator of myogenesis

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08654 MRLN Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus MRLN MGD MGI:1916813
Rattus norvegicus MRLN RGD RGD:6490783