2. Gene
  3. TTR - transthyretin Gene

TTR - transthyretin Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Macaca mulatta

Also known as TTR1

Gene ID: 705943 | Gene type: protein coding

About TTR

Primary_assembly 18: 50,937,580-50,965,956 reverse strand.Mmul_10:CM014353.1

This gene has 2 transcripts (splice variants), 177 orthologues and 3 paralogues.

TTR Products(1)

mRNA Protein Name
NM_001261679.1 NP_001248608.1 transthyretin precursor

TTR Protein Structure

Peptidase_M14NE-CP-C_like

Peptidase_M14NE-CP-C_like: cl21470 (26 - 146)

  • 0
  • 100
  • 147 a.a.
Protein Preferred Names Protein Names

transthyretin

transthyretin (prealbumin, amyloidosis type I)

Related Agents

Approval
Bioactive Molecules (10)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-132609 Patisiran sodium 99.09% Unkown
HY-14852 Tafamidis Inhibitor 99.93% Yes
HY-132608 Inotersen sodium 96.44% Unkown
HY-132589 Vutrisiran 97.37% Unkown
HY-132589A Vutrisiran sodium Inhibitor 97.37% Unkown
HY-14852A Tafamidis meglumine 99.79% Yes
HY-148089A Eplontersen sodium Inhibitor 96.95% Unkown
HY-112974 Inotersen Inhibitor 96.44% Unkown
HY-148089 Eplontersen Inhibitor 98.70% Unkown
HY-14852R Tafamidis (Standard) Inhibitor 99.24% Unkown
Clinical Phase
Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Phase
HY-109165 Acoramidis 98.47% Phase 3
HY-132590A Revusiran sodium Inhibitor 93.16% Phase 3
HY-109165A Acoramidis hydrochloride 98.70% Phase 3
HY-132590 Revusiran / Phase 3
HY-177650 Nucresiran Inhibitor 97.24% Phase 1
HY-177650A Nucresiran sodium Inhibitor / Phase 1
Pre-clinical Phase
Bioactive Molecules (22)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-113283 Homogentisic acid 99.68% Unkown
HY-N1957 Gamma-Mangostin 99.91% Unkown
HY-153609 AS-Patisiran sodium Inhibitor 95.10% Unkown
HY-W331198 Tralopyril Inducer 99.70% Unkown
HY-113950 Dichlorophenyl-ABA 99.79% Unkown
HY-153577 WT-TTR inhibitor 1 Inhibitor 98.03% Unkown
HY-RS15238 TTR Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-165604 C14-490 98% Unkown
HY-185504 Nexiguran / Unkown
HY-146137 Transthyretin-IN-1 / Unkown
HY-147366 RBP4 ligand-1 Inhibitor / Unkown
HY-14852S Tafamidis-d3 / Unkown
HY-155299 PITB Inhibitor / Unkown
HY-159658 TTR stabilizer 1 Modulator / Unkown
HY-161505 Transthyretin-IN-3 Inhibitor / Unkown
HY-P10615 Abz-YGGRASDQ-EDDnp / Unkown
HY-P11698 Guanidino-G-Clamp-PNA Inhibitor / Unkown
HY-RS15239 Ttr Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15240 Ttr Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-126927 TTR stabilizer L6 Modulator / Unkown
HY-160612 Transthyretin-IN-2 Inhibitor / Unkown
HY-176233 Transthyretin-IN-4 Inhibitor / Unkown
Inhibitory Antibodies (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P990734 Coramitug Inhibitor 99.00% Unkown
HY-P991128 Cliramitug 97.0% Unkown
HY-P991412 NI-301 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens TTR NCBI NCBI:7276
Macaca fascicularis TTR NCBI NCBI:101864775
Mus musculus TTR NCBI NCBI:22139
Rattus norvegicus TTR NCBI NCBI:24856