RBP4 ligand-1
RBP4 ligand-1 is a non-retinoid ligands for (RBP4) retinol-binding protein 4. The hRBP4SPA IC50 and RBP4-TTR FRET IC50 values are 0.23±0.11 and 0.13±0.12 μM in the radioligand binding assay and FRET assay, respectively.
For research use only. We do not sell to patients.
- CAS No.: 260553-24-0
- Formula: C18H18ClF3N4O2
- Molecular Weight:414.81
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Retinol-Binding Protein 4 (RBP4) is a physiological carrier of retinol (vitamin A) in blood, delivering retinol from the liver to peripheral tissues.RBP4 ligand-1 has the ability to disrupt the RBP4-TTR protein-protein interaction (hRPB4-TTR). The RBP4-TTR FRET IC50 is 0.13±0.12 μM in FRET assay[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 260553-24-0
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Molecular Weight 414.81
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Formula C18H18ClF3N4O2
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SMILES
FC(F)(C1=C(N2CCN(C(NC3=C(C=CC(Cl)=C3)OC)=O)CC2)N=CC=C1)F
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
RBP4 ligand-1 Related Classifications
HY-147366 Related Classifications
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