DPF3 - double PHD fingers 3 Gene

Also Known as CERD4; BAF45C; SMARCG3

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 8110

About DPF3

Cytogenetic location: 14q24.2 Genomic coordinates (GRCh38): 14:72,609,034-72,894,101 (from NCBI)

This gene has 14 transcripts (splice variants), 208 orthologues and 9 paralogues. Biased expression in ovary (RPKM 2.9), heart (RPKM 2.2) and 11 other tissues.

Summary

This gene encodes a member of the D4 protein family. The encoded protein is a transcription regulator that binds acetylated histones and is a component of the BAF chromatin remodeling complex. Alternate splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]

DPF3 Products (4)

mRNA Protein Name
NM_001280542.3 NP_001267471.1 zinc finger protein DPF3 isoform 2
NM_001280543.2 NP_001267472.1 zinc finger protein DPF3 isoform 3
NM_001280544.2 NP_001267473.1 zinc finger protein DPF3 isoform 4
NM_012074.5 NP_036206.3 zinc finger protein DPF3 isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32459350 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

DPF3 Protein Structure

Requiem_N

Requiem_N: N-terminal domain of DPF2/REQ. (13 - 84)

PHD

PHD: PHD-finger (319 - 363)

  • 0
  • 100
  • 200
  • 300
  • 378 a.a.
Protein Preferred Names Protein Names

zinc finger protein DPF3

  • BRG1-associated factor 45C

Related Diseases

Diseases Alias
Melanomatosis
Atrial Septal Defect 9

  • ASD9

  • Atrial Heart Septal Defect 9

  • Septal Defect, Atrial, Type 9
Tetralogy Of Fallot

  • TOF

  • Fallot Tetralogy

  • Ventricular Septal Defect With Pulmonary Stenosis Or Atresia, Dextraposition Of Aorta, And Hypertrophy Of Right Ventricle

  • Tetrad Of Fallot

  • Fallot Tetrad

  • Fallot Disease

  • Fallot Complex

  • Subpulmonic Stenosis, Ventricular Septal Defect, Overriding Aorta, And Right Ventricular Hypertrophy

  • Interventricular Septal Defect With Dextroposition Of Aorta, Pulmonary Stenosis And Hypertrophy Of Right Ventricle

  • Interventricular Septal Defect, In Tetralogy Of Fallot

  • Ventricular Septal Defect With Obstructed Right Ventricular Outflow

  • Tof - [Tetralogy Of Fallot]

  • Pulmonary Atresia With Ventricular Septal Defect [Fallot Type]

  • Pulmonary Atresia, Ventricular Septal Defect And Mapcas

  • Pulmonary Atresia With Ventricular Septal Defect And Systemic-To-Pulmonary Collateral Arteries [Fallot Type]
Hirschsprung Disease 1

  • Hirschsprung Disease

  • Aganglionic Megacolon

  • Hscr

  • Hirschsprung'S Disease

  • Congenital Megacolon

  • Congenital Intestinal Aganglionosis

  • Colonic Aganglionosis

  • Hirschsprung Disease, Susceptibility To, 1

  • Hirschsprung Disease, Protection Against

  • HSCR1

  • Mgc

  • Pelvirectal Achalasia

  • Total Intestinal Aganglionosis

  • Megacolon, Aganglionic

  • Macrocolon

  • Hscr 1

  • Hirschsprung Disease Type 1

  • Hirschsprung Disease, Type 1

  • Congenital Dilatation Of Colon

  • Aganglionosis

  • Congenital Aganglionic Megacolon

  • Aganglionosis Of Colon

  • Bowel Aganglionosis

  • Colon Aganglionosis

  • Hirschsprung Megacolon
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P4344 Met-Gly-Pro-AMC Substrate 99.74% Unkown
HY-RS03951 DPF3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta DPF3 VGNC VGNC:99198
Bos taurus DPF3 VGNC VGNC:28177
Felis catus DPF3 VGNC VGNC:61595
Mus musculus DPF3 MGD MGI:1917377
Rattus norvegicus DPF3 RGD RGD:1309052
Canis familiaris DPF3 VGNC VGNC:50524
Others DPF3 NCBI