hVEGF-IN-2
hVEGF-IN-2 (compound 19) is a selective VEGF (Flk-1) receptor tyrosine kinases (RTK) inhibitor with an IC50 value of 2.5 μM. hVEGF-IN-2 inhibits PDGF RTK activity with an IC50 value of 33.1 μM. hVEGF-IN-2 can be used for the development of RTK-specific agents.
For research use only. We do not sell to patients.
- CAS No.: 186610-88-8
- Formula: C19H18N2O2
- Molecular Weight:306.36
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All VEGFR Isoforms
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Biological Activity
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VEGFR1 2.5 μM (IC50) |
PDGF 33.1 μM (IC50) |
hVEGF-IN-2 (0-100 μM) shows the inhibitory activities to particular RTKs at the cellular level with IC50 values of 2.5, 33.1, >100, >100 and >100 nM for VEGF, PDGF, EGF, HER-2 and IGF-1, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 186610-88-8
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Molecular Weight 306.36
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Formula C19H18N2O2
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SMILES
O=C1NC2=C(C=CC=C2)/C1=C/C3=CC=C(N4CCOCC4)C=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (269 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)