186610-88-8
186610-88-8
Chemical Structure
hVEGF-IN-2
- CAS. Nr.: 186610-88-8
- Formula:C19H18N2O2
- Molecular Weight:306.36
IUPAC Name: (Z)-3-(4-morpholinobenzylidene)indolin-2-one
InChIKey: FWFISWZSIAJQSO-LGMDPLHJSA-N
SMILES: O=C1NC2=C(C=CC=C2)/C1=C/C3=CC=C(N4CCOCC4)C=C3
Biological Activity: hVEGF-IN-2 (compound 19) is a selective VEGF (Flk-1) receptor tyrosine kinases (RTK) inhibitor with an IC50 value of 2.5 μM. hVEGF-IN-2 inhibits PDGF RTK activity with an IC50 value of 33.1 μM. hVEGF-IN-2 can be used for the development of RTK-specific agents[1].
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hVEGF-IN-2 | hVEGF-IN-2 (compound 19) is a selective VEGF (Flk-1) receptor tyrosine kinases (RTK) inhibitor with an IC50 value of 2.5 μM. hVEGF-IN-2 inhibits PDGF RTK activity with an IC50 value of 33.1 μM. hVEGF-IN-2 can be used for the development of RTK-specific agents. | |||||||||||||||||||||
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References
Keywords
