BMS-505130 fumarate
BMS-505130 fumarate is a potent, selective and orally active serotonin transport inhibitor with a Ki for binding to the serotonin transporter of 0.18 nM (Ki for norepinephrine and dopamine transporters of 4.6 and 2.1 μM, respectively). BMS-505130 fumarate can be used for the research of neurological disease, such as depression.
For research use only. We do not sell to patients.
- CAS No.: 859230-84-5
- Formula: C19H21N3O4
- Molecular Weight:355.39
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
BMS-505130 fumarate (1-30 mg/kg, i.p. or p.o.) produces a significant decrease in immobility time in depressant mice[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Depressant mice[1]
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Dosage:1, 3, 10 and 30 mg/kg
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Administration:Intraperitoneally injection or Orally administration
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Result:Decreased immobility time in tail suspension test.
Chemical Information
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CAS No. 859230-84-5
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Molecular Weight 355.39
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Formula C19H21N3O4
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SMILES
O=C(O)/C=C\C(O)=O.CN(C)C[C@@H]1[C@@H](C2=CNC3=CC=C(C#N)C=C23)C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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