258 Results for "

ig-

" in MedChemExpress (MCE) Product Catalog:
Products (258)

258 Results for "ig-" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-P99459
CAS No.: 909110-25-4
Synonyms: BG 9924; TT-47

Target:  

TNF Receptor CXCR

Research Areas:  

Inflammation/Immunology

Baminercept (BG 9924; TT-47) is an Ig fusion protein targeting the lymphotoxin β receptor (LTβR). Baminercept effectively regulates subsets of circulating immune cells by inhibiting LIGHT, LT-α1β2 and their receptors. Baminercept also increases blood lymphocyte counts and reduces plasma CXCL13 levels. Baminercept carries a high risk of hepatotoxicity. Baminercept can be used in research on rheumatoid arthritis and primary Sjögren's syndrome .
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2
2 Cited Publications
Cat. No.: HY-103358
CAS No.: 257292-29-8
Purity:  99.63%
Target:  

P-selectin

Research Areas:  

Inflammation/Immunology

KF38789 is a selective inhibitor of P-selectin-PSGL-1 binding. KF38789 inhibits the binding of U937 cells to immobilized P-selectin immunoglobulin G chimeric protein (P-selectin-Ig) with an IC50 value of 1.97 μM .
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2
2 Cited Publications
Cat. No.: HY-P73904
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ig gamma chain C region; igG
Species:  
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2
2 Cited Publications
Cat. No.: HY-P70669
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ig gamma-4 chain C region,igG4 Fc
Species:  
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1
1 Cited Publications
Cat. No.: HY-108801A
CAS No.: 862111-32-8
Purity:  97.66%

Target:  

VEGFR

Research Areas:  

Cardiovascular Disease Cancer

Aflibercept (VEGF Trap) is a soluble decoy VEGFR constructed by fusing the Ig domains of VEGFR1 and VEGFR2 with the Fc region of human IgG1. Aflibercept inhibits VEGF signaling by reducing VEGF-regulated processes. Aflibercept can be used for thr research of age-related macular degeneration (AMD) and cardiovascular disease .
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1
1 Cited Publications
Cat. No.: HY-108801
CAS No.: 862111-32-8
Synonyms: VEGF Trap; VEGF-TRAPR1R2; VEGF-trapR1

Target:  

VEGFR

Aflibercept (VEGF Trap) is a soluble decoy VEGFR constructed by fusing the Ig domains of VEGFR1 and VEGFR2 with the Fc region of human IgG1. Aflibercept inhibits VEGF signaling by reducing VEGF-regulated processes. Aflibercept can be used for thr research of age-related macular degeneration (AMD) and cardiovascular disease .
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1
1 Cited Publications
Cat. No.: HY-NP006
CAS No.: 308083-69-4
Synonyms: SPA
Protein A (SPA) is an immunoglobulin (Ig)-binding protein that exists on the bacterial surface and can be freely secreted into the extracellular environment. Protein A blocks opsonophagocytosis and induces B cell apoptosis in vitro by binding to the Fc region of antibodies and the Fab region of B cell receptors. Protein A can form toxic immune complexes with IgG, thereby inducing leukocyte necrosis. Protein A contributes to the virulence expression of Staphylococcus aureus. Protein A triggers allergic reactions in IgG-pretreated mouse models. Protein A can be used in studies related to immune system diseases .
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1
1 Cited Publications
Cat. No.: HY-P99446
CAS No.: 845264-92-8
Synonyms: TACI-ig; TACI-Fc 5

Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

Atacicept (TACI-Ig) is a is a recombinant fusion protein containing the extracellular, ligand-binding portion of the TACI receptor and the Fc portion of human IgG. Atacicept inhibits B cell stimulation by binding to B lymphocyte stimulator and a proliferation-inducing ligand. Atacicept can be used in research of B-cell autoimmune disease .
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1
1 Cited Publications
Cat. No.: HY-P99040
CAS No.: 1969313-51-6
Synonyms: JNJ-61610588; CI-8993; VSTB112

Target:  

VISTA

Research Areas:  

Cancer

Onvatilimab (JNJ-61610588) is a human IgG1κ anti-VISTA (V-domain Ig Suppressor of T-cell Activation) monoclonal antibody. Onvatilimab can be used in colorectal cancer research .
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1
1 Cited Publications
Cat. No.: HY-P74525A
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Transforming growth factor-beta-induced protein ig-h3; Beta ig-h3; RGD-CAP; BigH3
Species:  
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1
1 Cited Publications
Cat. No.: HY-P77695
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ig epsilon chain C region; igE
Species:  
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1
1 Cited Publications
Cat. No.: HY-P70771
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ig gamma-4 chain C region,igG4 Fc
Species:  
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1
1 Cited Publications
Cat. No.: HY-P72603
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ig gamma-2 chain C region; igG2A Fc
Species:  
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1
1 Cited Publications
Cat. No.: HY-P70796
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ig gamma-1 chain C region; igHG1
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1
1 Cited Publications
Cat. No.: HY-P79127
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Sialic acid-binding ig-like lectin 11; SigLEC11; Sialic acid-binding lectin 11; Siglec-11; Sialic Acid Binding ig-like Lectin 11
Species:  
Source:  
CHO
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1
1 Cited Publications
Cat. No.: HY-P70742
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Sialic acid-binding ig-like lectin 15; Siglec-15; CD33 antigen-like 3; CD33L3
Species:  
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1
1 Cited Publications
Cat. No.: HY-P70933
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Heat shock protein beta-8; HspB8; Alpha-crystallin C chain; E2-induced gene 1 protein; Protein kinase H11; Small stress protein-like protein HSP22; HSPB8; CRYAC; E2ig1; HSP22
Species:  
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Cat. No.: HY-P99386
CAS No.: 1205533-60-3
Synonyms: MNRP-1685A

Research Areas:  

Cancer

Vesencumab (MNRP-1685A) is IG1 antibody against neuropilin-1 (NRP-1). Vesencumab binds to NRP-1 and prevents the subsequent coupling of NRP-1 to VEGFR-2. Vesencumab has anti-angiogenic and anti-neoplastic activities. Vesencumab can be used in the research of metastatic solid tumors, including ovarian cancer .
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Cat. No.: HY-122663A
Purity:  99.88%
Target:  

TNF Receptor Apoptosis

Research Areas:  

Metabolic Disease

BIO8898 is a potent CD40-CD154 inhibitor. BIO8898 inhibits soluble CD40L binding to CD40-Ig with an IC50 value of 25 µM. BIO8898 inhibits CD40L-induced apoptosis .
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Cat. No.: HY-P99868
CAS No.: 1831098-91-9
Synonyms: MGD 011

Target:  

CD19 CD3

Research Areas:  

Cancer

Duvortuxizumab (MGD 011) is a chimeric humanized IG antibody targeting CD19 and CD3E .
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