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Cat. No.: HY-118736

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Ganodermic acid S

Ganodermic acid S is an oxygenated triterpenoid, that can be isolated from the Chinese medicinal fungus Ganoderma lucidum (Fr.) Karst (Polyporaceae). Ganodermic acid S exerts a concentration dependent inhibition on the response of human gel-filtered platelets (GFP) to U-46619 (HY-108566), a thromboxane (TX) A2 mimetic.

For research use only. We do not sell to patients.

CAS No.: 112430-63-4
Formula: C₃₄H₅₀O₆
Molecular Weight:554.76

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

Ganodermic acid S Chemical Structure

CAS No.: 112430-63-4

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Cellular Effect

Cell Line	Type	Value	Description	References
Vero	IC₅₀	32 μM Compound: 35	Cytotoxicity against African green monkey Vero cells by GFP based microplate assay Cytotoxicity against African green monkey Vero cells by GFP based microplate assay	[PMID: 28504879]

In Vitro

Ganodermic acid S inhibits U46619-activated platelet aggregation. Ganodermic acid S strongly inhibits U46619-induced diacylglycerol formation, Ca²⁺ mobilization, granule secretion, and arachidonic acid release^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 112430-63-4
Molecular Weight 554.76
Formula C₃₄H₅₀O₆
SMILES

CC1([C@H](CC[C@@]2(C3=CC[C@@]4([C@H](C[C@@H]([C@]4(C3=CC[C@@]12[H])C)OC(C)=O)[C@@H](CC/C=C(C(O)=O)\C)C)C)C)OC(C)=O)C
Structure Classification
- Terpenoids
- Triterpenes
- Ketones, Aldehydes, Acids
Initial Source
- Microorganisms
Ganoderma lucidum
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Su CY, et al. Differential effects of ganodermic acid S on the thromboxane A2-signaling pathways in human platelets. Biochem Pharmacol. 1999 Aug 15;58(4):587-95. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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