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製品番号: HY-100295

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(4-Acetamidocyclohexyl) nitrate

(別名: BM121307)

(4-Acetamidocyclohexyl) nitrate (BM121307) is a guanylate cyclase activator.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 137213-91-3
分子式: C₈H₁₄N₂O₄
分子量:202.21

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

(4-Acetamidocyclohexyl) nitrate 構造式

CAS 番号: 137213-91-3

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

(4-Acetamidocyclohexyl) nitrate (BM121307) is a guanylate cyclase activator.

体内実験

The elimination of BM121307 and its metabolites via urine and feces amount to 76.5% after oral application, and to 80.7% of the applied dose after intravenous application. The major amount of radioactivity is eliminated via urine (69.4% and 73.6% of the dose, respectively), whereas the fecal elimination is found to be negligible. Investigations of the urinary samples show that the drug is metabolized to a high percentage trans-N-(4-Hydroxycyclohexyl) acetamide is the main metabolite; 73% of the radioactive compounds (after p.o.-administration and 69% after intravenous application could be identified as the alcohol of BM121307; the amounts of the drug totaled 9% and 13%, respectively^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

CAS 番号 137213-91-3
分子量 202.21
分子式 C₈H₁₄N₂O₄
SMILES

CC(N[C@@H]1CC[C@@H](O[N+]([O-])=O)CC1)=O
別名

BM121307
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

プロトコル

Animal Administration^[1]

Dogs^[1]

The biotransformation of BM121307 in the dog is examined after oral and intravenous administration. For that purpose, the organic nitrate is synthesized as radioactive [¹⁴C]- and as [¹³C]-labeled compounds. The defined isotopic mixture is administered to the dogs. Within the examined period of 168 h, the elimination of BM121307 is measured^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (267 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Zell C, et al. Biotransformation of the organic nitrate trans-N-(4-nitroxycyclohexyl)acetamide in dogs. Arzneimittelforschung. 1994 Sep;44(9):1021-8. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

(4-Acetamidocyclohexyl) nitrate

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(4-Acetamidocyclohexyl) nitrate

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Lificiguat

Nelociguat

NS-2028

Vericiguat (Standard)

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Praliciguat

Riociguat (Standard)

生物活性

化学情報

プロトコル

純度とドキュメンテーション

参考文献

Calculators

Help & FAQs

(4-Acetamidocyclohexyl) nitrate

Vericiguat

Linaclotide

Riociguat

Cinaciguat

BAY 41-2272

Lificiguat

Nelociguat

NS-2028

Vericiguat (Standard)

Cinaciguat hydrochloride

Praliciguat

Riociguat (Standard)

生物活性

化学情報

プロトコル

純度とドキュメンテーション

参考文献

Calculators

Help & FAQs

(4-Acetamidocyclohexyl) nitrate 関連分類

HY-100295 関連分類