1. GPCR/G Protein
  2. Guanylate Cyclase

BAY 41-2272 

Cat. No.: HY-12376 Purity: 99.93%
Data Sheet SDS Handling Instructions

BAY 41-2272 is a soluble guanylate cyclases (sGC) activator.

For research use only. We do not sell to patients.
BAY 41-2272 Chemical Structure

BAY 41-2272 Chemical Structure

CAS No. : 256376-24-6

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO $88 In-stock
5 mg $80 In-stock
10 mg $140 In-stock
25 mg $290 In-stock
50 mg $460 In-stock
100 mg $820 In-stock
200 mg   Get quote  
500 mg   Get quote  

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Description

BAY 41-2272 is a soluble guanylate cyclases (sGC) activator. Target: guanylate cyclase BAY 41-2272 is a recently introduced novel orally available agent that directly stimulates soluble guanylate cyclase (sGC) and sensitizes it to its physiological stimulator, nitric oxide. BAY 41-2272 is a promising new therapeutic agent that goes beyond current therapeutic agents. BAY 41-2272 acts as an arterial vasodilator, resulting in a reduction of MAP and pulmonary artery pressure and a decrease in SVR and renal vascular resistance. BAY 41-2272 reduces pulmonary capillary wedge pressure in the absence of a decrease in right atrial pressure. [2]

References
Molecular Weight

360.39

Formula

C₂₀H₁₇FN₆

CAS No.

256376-24-6

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

DMSO: 17.5 mg/mL

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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Product Name:
BAY 41-2272
Cat. No.:
HY-12376
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