sn-Glycerol 3-phosphate
sn-Glycerol 3-phosphate is an important intermediate in glycolysis and lipid metabolism. The cytosolic sn-Glycerol 3-phosphate dehydrogenase (GPDH) consumes NADH to generate sn-Glycerol 3-phosphate from dihydroxyacetone phosphate (DHAP). Glyceroneogenesis is an important supplier of sn-Glycerol 3-phosphate for lipid metabolism.
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- 純度: 98.0%
- CAS 番号: 17989-41-2
- 分子式: C3H9O6P
- 分子量:172.07
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保管条件:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
Endogenous Metabolite アイソフォーム固有の製品をすべて表示
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生物活性
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Human Endogenous Metabolite |
The cytosolic GPDH consumes NADH to generate sn-Glycerol 3-phosphate from dihydroxyacetone phosphate (DHAP), and the resulting sn-Glycerol 3-phosphate passes through the permeable mitochondrial outer membrane. sn-Glycerol 3-phosphate is reoxidized to DHAP at the outer surface of the inner mitochondrial membrane by the mitochondrial FAD-GPDH, which donates the electrons to the mitochondrial ubiquinone pool. The DHAP is subsequently channeled back to the cytosolic compartment[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 17989-41-2
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性状 Solid
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分子量 172.07
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分子式 C3H9O6P
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Color White to off-white
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SMILES
O[C@H](CO)COP(O)(O)=O
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別名
sn-グリセロール3-リン酸 リチウム塩
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
H2O : 125 mg/mL (726.45 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
For the following dissolution methods, please prepare the working solution directly:
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: PBS
Solubility: 25 mg/mL (145.29 mM); Clear solution; Need ultrasonic and warming
純度とドキュメンテーション
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データシート (271 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Frasson D, et al. The sympathetic nervous system regulates the three glycerol-3P generation pathways in white adipose tissue of fasted, diabetic and high-protein diet-fed rats. Metabolism. 2012 Oct;61(10):1473-85. [Content Brief]
[2]. Shen W, et al. Involvement of a glycerol-3-phosphate dehydrogenase in modulating the NADH/NAD+ ratio provides evidence of a mitochondrial glycerol-3-phosphate shuttle in Arabidopsis. Plant Cell. 2006 Feb;18(2):422-41. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 5.8116 mL | 29.0579 mL | 58.1159 mL | 145.2897 mL |
| 5 mM | 1.1623 mL | 5.8116 mL | 11.6232 mL | 29.0579 mL | |
| 10 mM | 0.5812 mL | 2.9058 mL | 5.8116 mL | 14.5290 mL | |
| 15 mM | 0.3874 mL | 1.9372 mL | 3.8744 mL | 9.6860 mL | |
| 20 mM | 0.2906 mL | 1.4529 mL | 2.9058 mL | 7.2645 mL | |
| 25 mM | 0.2325 mL | 1.1623 mL | 2.3246 mL | 5.8116 mL | |
| 30 mM | 0.1937 mL | 0.9686 mL | 1.9372 mL | 4.8430 mL | |
| 40 mM | 0.1453 mL | 0.7264 mL | 1.4529 mL | 3.6322 mL | |
| 50 mM | 0.1162 mL | 0.5812 mL | 1.1623 mL | 2.9058 mL | |
| 60 mM | 0.0969 mL | 0.4843 mL | 0.9686 mL | 2.4215 mL | |
| 80 mM | 0.0726 mL | 0.3632 mL | 0.7264 mL | 1.8161 mL | |
| 100 mM | 0.0581 mL | 0.2906 mL | 0.5812 mL | 1.4529 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
sn-Glycerol 3-phosphate 関連分類
HY-113128 関連分類
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