HK-2-IN-2
HK2-IN-2 (Compound 26) is a Hexokinase 2 inhibitor that demonstrates significant anti-tumor activity by targeting microtubules and Hexokinase 2, with an IC50 value of 0.764 μM against MD-MBA-231 cells. HK2-IN-2 effectively inhibits the activity of Hexokinase 2, leading to the accumulation of Reactive Oxygen Species and dysfunction of the mitochondrial membrane potential (MMP), thereby promoting apoptosis and blocking the cell cycle.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 3056278-80-6
- 分子式: C26H22N4O6S
- 分子量:518.54
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
|
Hexokinase 2 |
化学情報
-
CAS 番号 3056278-80-6
-
分子量 518.54
-
分子式 C26H22N4O6S
-
SMILES
O=C(C1=CC=CN=C1)/C=C/C2=CN(S(=O)(C3=CC=C([N+]([O-])=O)C=C3)=O)C4=C2C=C(N5CCOCC5)C=C4
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)