B I09 (Standard)
B I09 (Standard) is the analytical standard of B I09 (HY-107400). This product is intended for research and analytical applications. B I09 is an IRE-1 RNase inhibitor, with an IC50 of 1230 nM.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 1607803-67-7
- 分子式: C16H17NO5
- 分子量:303.31
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
IC50: 1230 nM (IRE-1 RNase)[1].
化学情報
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CAS 番号 1607803-67-7
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分子量 303.31
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分子式 C16H17NO5
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SMILES
OC1=CC=C(C2=C(CNCC2)C3=O)C(O3)=C1C4OCCCO4
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Ranatunga S, et al. Synthesis of novel tricyclic chromenone-based inhibitors of IRE-1 RNase activity. J Med Chem. 2014 May 22;57(10):4289-301. [Content Brief]
[2]. Tang CH, et al. Inhibition of ER stress-associated IRE-1/XBP-1 pathway reduces leukemic cell survival. J Clin Invest. 2014 Jun;124(6):2585-98. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)