Leupeptin acid
Leupeptin acid is a peptide byproduct present in the fermentation product of Streptomyces roseus MA839-A1, and also an intermediate in leupeptin biosynthesis. Leupeptin acid serves as a substrate for leupeptin acid reductase to generate Leupeptin (HY-18234).
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- CAS 番号: 24125-28-8
- 分子式: C20H38N6O5
- 分子量:442.55
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
Endogenous Metabolite アイソフォーム固有の製品をすべて表示
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生物活性
Leupeptin acid is reduced to Leupeptin (HY-18234) by solubilized leupeptin acid reductase from Streptomyces roseus MA839-A1 in an ATP- and NADPH-dependent manner; the enzyme has Km values of 4.2 × 10-5 M for ATP and 1.3 × 10-6 M for NADPH, and is strongly suppressed by leupeptin and antipain rather than elastatinal[2].
Leupeptin acid is biosynthesized as an intermediate to form leupeptin by the combined leucine acyltransferase and leupeptin acid synthetase-reductase complex from Streptomyces roseus MA839-A1 using acetyl-CoA, L-leucine (HY-N0486) and L-arginine (HY-N0455) as substrates[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 24125-28-8
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分子量 442.55
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分子式 C20H38N6O5
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SMILES
N=C(NCCC[C@H](NC([C@@H](NC([C@@H](NC(C)=O)CC(C)C)=O)CC(C)C)=O)C(O)=O)N
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Leupeptin acid 関連分類
HY-122476 関連分類
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