country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

製品番号: HY-N10430

Copy Link Print Information

Patentiflorin A

Patentiflorin A is a potent, broadspectrum HIV-1 inhibitor. Patentiflorin A also inhibits HIV drug-resistant strains.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 857050-63-6
分子式: C₂₇H₂₆O₁₁
分子量:526.49

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

Patentiflorin A 構造式

CAS 番号: 857050-63-6

容量

価格（税別）

在庫状況

数量

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性
- 製品説明
- IC₅₀ & Target
- Cellular Effect
- 体外実験
化学情報
純度とドキュメンテーション
参考文献
Calculators
Help & FAQs
関連分類
Bioz

生物活性

製品説明

Patentiflorin A is a potent, broadspectrum HIV-1 inhibitor. Patentiflorin A also inhibits HIV drug-resistant strains^[1].

IC₅₀ & Target

HIV-1

HIV アイソフォーム固有の製品をすべて表示 :

Cellular Effect

Cell Line	Type	Value	Description	References
HCT-116	IC₅₀	0.012 μM Compound: 3, patentiflorin A	Cytotoxicity against human HCT116 cells Cytotoxicity against human HCT116 cells	[PMID: 15921419]
HCT-116	IC₅₀	0.99 μM Compound: 2	Cytotoxicity against human HCT116 cells after 72 hrs by sulforhodamine B and MTT assay Cytotoxicity against human HCT116 cells after 72 hrs by sulforhodamine B and MTT assay	[PMID: 22119124]
HEK293	CC₅₀	>80 μM Compound: Patentiflorin A	Cytotoxicity against HEK293 cells incubated for 72 hrs by MTT assay Cytotoxicity against HEK293 cells incubated for 72 hrs by MTT assay	[PMID: 38875806]
K562	IC₅₀	1.43 μM Compound: 2	Cytotoxicity against human K562 cells after 72 hrs by sulforhodamine B and MTT assay Cytotoxicity against human K562 cells after 72 hrs by sulforhodamine B and MTT assay	[PMID: 22119124]
K562	IC₅₀	16.14 μM Compound: 2	Cytotoxicity against adriamycin-selected multi drug-resistant human K562 cells after 72 hrs by sulforhodamine B and MTT assay Cytotoxicity against adriamycin-selected multi drug-resistant human K562 cells after 72 hrs by sulforhodamine B and MTT assay	[PMID: 22119124]
KB	IC₅₀	0.004 μM Compound: 3, patentiflorin A	Cytotoxicity against human KB cells Cytotoxicity against human KB cells	[PMID: 15921419]
KB	IC₅₀	0.093 μM Compound: 2	Cytotoxicity against human KB cells after 72 hrs by sulforhodamine B and MTT assay Cytotoxicity against human KB cells after 72 hrs by sulforhodamine B and MTT assay	[PMID: 22119124]
KB	IC₅₀	0.573 μM Compound: 2	Cytotoxicity against vincristine-selected multi drug-resistant human KB cells after 72 hrs by sulforhodamine B and MTT assay Cytotoxicity against vincristine-selected multi drug-resistant human KB cells after 72 hrs by sulforhodamine B and MTT assay	[PMID: 22119124]
MCF7	IC₅₀	0.003 μM Compound: 3, patentiflorin A	Cytotoxicity against doxorubicin-sensitive human MCF7 cells Cytotoxicity against doxorubicin-sensitive human MCF7 cells	[PMID: 15921419]
MCF7	IC₅₀	0.04 μM Compound: 3, patentiflorin A	Cytotoxicity against doxorubicin-resistant human MCF7 cells Cytotoxicity against doxorubicin-resistant human MCF7 cells	[PMID: 15921419]
MCF7	IC₅₀	0.44 μM Compound: 2	Cytotoxicity against human MCF7 cells after 72 hrs by sulforhodamine B and MTT assay Cytotoxicity against human MCF7 cells after 72 hrs by sulforhodamine B and MTT assay	[PMID: 22119124]
PBMC	CC₅₀	75 μM Compound: 1, Natural	Cytotoxicity against human PBMC after 48 hrs by CellTiter 96 AQueous one solution cell proliferation assay Cytotoxicity against human PBMC after 48 hrs by CellTiter 96 AQueous one solution cell proliferation assay	[PMID: 28613071]

体外実験

Patentiflorin A shows inhibition activity with IC₅₀ values of 32, 31, 30, 32, 108, 61 and 47 nM against Bal: M-Tropic, 89.6: Dual-Tropic, SF162: M-Tropic, Lav.04: T-Tropic, HIV-1_LAV, HIV-1_1617-1 and HIV-1_N119, respectively^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

CAS 番号 857050-63-6
分子量 526.49
分子式 C₂₇H₂₆O₁₁
SMILES

O=C1C2=C(C3=CC=C(OCO4)C4=C3)C5=CC(OC)=C(OC)C=C5C(O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)C)O)O)O)=C2CO1
Structure Classification
- Phenylpropanoids
- Lignans
Initial Source
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (273 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Zhang HJ, et al. Potent Inhibitor of Drug-Resistant HIV-1 Strains Identified from the Medicinal Plant Justicia gendarussa. J Nat Prod. 2017 Jun 23;80(6):1798-1807. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

お問い合わせ在庫あり

Other size

お問い合わせ

Amount: USD 0.00

生物活性
- 製品説明
- IC₅₀ & Target
- 体外実験
化学情報
純度とドキュメンテーション
参考文献

製品名:
製品番号:
数量:
日本の代理先をお選びください:

製品名:
CAS 番号:
生物種:
純度:
数量:

Patentiflorin A

HIV アイソフォーム固有の製品をすべて表示

生物活性

化学情報

純度とドキュメンテーション

参考文献

Calculators

Help & FAQs

Patentiflorin A 関連分類

HY-N10430 関連分類