PLK3-IN-1
PLK3-IN-1 is a selective Polo-like kinase 3 (PLK3) inhibitor with a human PLK3 IC50 of 5 nM. PLK3-IN-1 can be used for cancer research.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C27H29FN8O
- 分子量:500.57
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
PLK3-IN-1 (Compound 9) potently inhibits purified PLK3 with an IC50 of 0.005 μM, and exhibits 1000-fold selectivity over PLK1 and 60-fold selectivity over PLK2 in a biochemical kinase inhibition assay[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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分子量 500.57
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分子式 C27H29FN8O
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SMILES
CN1CCC[C@H](C1)C2=CNC3=CC=C(C=C32)NC4=NC=C(C(N5CCN(C(C5)=O)C6=CC=CC=N6)=N4)F
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)