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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
16 Results for "
Aggression
" in MedChemExpress (MCE) Product Catalog:
Products (16)
16 Results for "Aggression" in MCE Product Catalog:
8
8 Publications Verification
Target:
研究分野:
L-368,899 hydrochloride is a potent, selective, orally bioavailable, non-peptide oxytocin receptor antagonist, with IC50s of 8.9 nM and 26 nM for rat uterus and human uterus oxytocin receptor, respectively. L-368,899 hydrochloride used as a tocolytic agent .
2
Category:
Human Gut Microbiota Metabolites Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields
Target:
1
1 Cited Publications
別名: Dehydroepiandrosterone 3-acetate; DHEA acetate
Category:
Target:
1
1 Cited Publications
製品番号: HY-N2411
CAS 番号: 60314-89-8
Target:
製品番号: HY-W004305
CAS 番号: 629-80-1
別名: Palmitaldehyde
製品番号: HY-178323
CAS 番号: 3048608-87-0
Target:
研究分野:
MW073 is a highly selective and orally active 5-HT2BR antagonist (IC50 =70 nM). MW073 exerts its effects by concentration-dependently inhibiting receptor activity and β-arrestin-1 recruitment. MW073 ameliorates synaptic plasticity and behavioral deficits, including aggression, in Alzheimer’s disease (AD) mouse models. MW073 can be used for Alzheimer’s disease (AD) research [1][2].
製品番号: HY-133171A
CAS 番号: 126924-38-7
Target:
研究分野:
(S)-Norfluoxetine, a S enantiomer of Norfluoxetine (HY-135556), is a selective serotonin reuptake inhibitor. (S)-Norfluoxetine can increase allopregnanolone levels and reduce aggression in socially isolated mice .
製品番号: HY-W004305R
CAS 番号: 629-80-1
別名: Palmitaldehyde (Standard)
別名: Dehydroepiandrosterone 3-acetate (Standard); DHEA acetate (Standard)
Target:
研究分野:
Dehydroisoandrosterone 3-acetate (Standard) is the analytical standard of Dehydroisoandrosterone 3-acetate. This product is intended for research and analytical applications. Dehydroepiandrosterone 3-acetate is a testosterone/estrogen precursor and known modulator of vertebrate aggression.
Target:
製品番号: HY-103403
CAS 番号: 156907-84-5
別名: PNU96391 hydrochloride
Target:
研究分野:
(-)-OSU6162 (PNU96391) hydrochloride is a dopamine stabilizer. (-)-OSU6162 hydrochloride acts as partial agonist at 5-HT2A and is a dopamine D2 antagonist. (-)-OSU6162 hydrochloride can be used for the research of aggression and irritability .
製品番号: HY-W673589
CAS 番号: 1561-02-0
別名: 2-Me-C26
Target:
研究分野:
2-Methylhexacosane is a saturated hydrocarbon and an insect pheromone. It has been found in the cuticle of M. dasystomus females, but not males, where it contributes to the mating behavior of males, as well as in D. melanogaster females where it modulates aggression of males towards females. 2-methylhexacosane has also been found in yellow jacket (V. vulgaris) trail extracts.
製品番号: HY-113413R
CAS 番号: 645-65-8
別名: Imidazolyl-4-acetic acid (Standard)
製品番号: HY-W004305S
CAS 番号: 2703602-66-6
別名: Palmitaldehyde-d5
製品番号: HY-108677R
CAS 番号: 160312-62-9
Target:
研究分野:
L-368,899 hydrochloride (Standard) is the analytical standard of L-368,899 hydrochloride (HY-108677). This product is intended for research and analytical applications. L-368,899 hydrochloride is a potent, selective, orally bioavailable, non-peptide oxytocin receptor antagonist, with IC50s of 8.9 nM and 26 nM for rat uterus and human uterus oxytocin receptor, respectively. L-368,899 hydrochloride used as a tocolytic agent .
製品番号: HY-L121
424 compounds
5-HT receptors, also called Serotonin receptors, are a group of G protein-coupled receptors (GPCRs) and ligand-gated ion channels (LGICs) found in the central and peripheral nervous systems. These receptors are now classified into seven families, 5-HT1–7, comprising a total of 14 structurally and pharmacologically distinct mammalian 5-HT receptor subtypes. The 5-HT receptors influence various biological and neurological processes such as aggression, anxiety, appetite, cognition, learning, memory, mood, nausea, sleep, andthermoregulation. The serotonin receptors are the target of a variety of pharmaceutical drugs, including many antidepressants, antipsychotics, anorectics, antiemetics, gastroprokinetic agents, antimigraine agents, hallucinogens, and entactogens.
MCE 5-HT Receptor Compound Library consists of 424 5-HT receptor inhibitors and activators, which can be used for neuropsychiatric disorders drugs discovery.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
